158697-66-6 Usage
General Description
Risperidone impurity B, also known as 9-hydroxyrisperidone, is a chemical impurity that can be found in the anti-psychotic medication Risperidone. It is a metabolite of Risperidone and is formed in the body through the action of the enzyme CYP2D6. Risperidone impurity B is considered a major metabolite of Risperidone and contributes to the therapeutic effects and side effects of the medication. It is important to monitor the levels of this impurity in the body to ensure the safe and effective use of Risperidone.
Check Digit Verification of cas no
The CAS Registry Mumber 158697-66-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,8,6,9 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 158697-66:
(8*1)+(7*5)+(6*8)+(5*6)+(4*9)+(3*7)+(2*6)+(1*6)=196
196 % 10 = 6
So 158697-66-6 is a valid CAS Registry Number.
158697-66-6Relevant articles and documents
A PROCESS FOR THE PREPARATION OF ANTIPSYCHOTIC RISPERIDONE
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Page 5, (2008/06/13)
This invention relates to a process for the preparation of antipsychotic risperidone (Formula I); which comprises reacting 3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido-[1,2-a]pyrimidin-4-one (Formula II); with 4-(2,4-difluorobenzoyl)piperidine oxime (Formula III); to form oxime (Formula IV); and in situ cyclization of oxime (Formula IV) to form risperidone (Formula I) in a solvent selected from the group consisting of acetonitrile, N,N-dimetylformamide and methyl isobutyl ketone.