1589-66-8Relevant articles and documents
THE BIOSYNTHESIS OF THE ALKALOIDS OF STEPHANIA GLABRA (ROXB.) MIERS
Bhakuni, Dewan S.,Gupta, Sandeep,Jain, Sudha
, p. 4003 - 4010 (1983)
Tracer experiments show that the tetrhydroprotoberberines stepholidine (14), corydalmine (15), capaurine (19) and corynoxidine (20) are stereospecifically biosynthesized from (S)-reticuline (22) whereas the bisbenzylisoquinoline alkaloids cycleanine (52),
Atorvastatin, an HMG-CoA reductase inhibitor and efficient lipid-regulating agent. Part I. Synthesis of ring-labeled [14C]atorvastatin
Woo, Peter W. K.,Hartman, Jon,Huang, Yun,Nanninga, Thomas,Bauman, Kelvin,Butler, Donald E.,Rubin, John R.,Lee, Helen T.,Huang, Che C.
, p. 121 - 127 (2007/10/03)
Pyrrole-ring labeled [14C]atorvastatin (Lipitor, CI-981), [R-(R(*),R(*))]-2(4-fluorophenyl)-β,γ-dihydroxy-5-(1-methylethyl)-3-phenyl -4-[(phenylamino)-carbonyl]-1H-[3-14C]pyrrole-1-heptanoic acid calcium salt (2:1), was synthesized i
BIOSYNTHESIS OF (+)-, (-)- AND (+/-)-TETRAHYDROPALMATINES
Bhakuni, Dewan S.,Jain, Sudha,Gupta, Sandeep
, p. 1591 - 1594 (2007/10/02)
Specific incorporation of didehydroreticuline and reticuline into (+/-)-, (+)-, and (-)-tetrahydropalmatines in Cocculus laurifolius and of (R)- and (S)-reticulines into (R)- and (S)-tetrahydropalmatines respectively has been demonstrated.Feeding of 3H,4'-methoxy-14C>reticuline suggested that reticuline was not converted in the plants into didehydroreticuline and racemisation of optically active forms of tetrahydropalmatine did not take place via dehydrotetrahydropalmatine.