15964-81-5

Basic information

• Product Name: Methyl 3-hydroxy-4-methoxyphenylacetate, 99%
• Synonyms: Methyl 3-hydroxy-4-methoxyphenylacetate, 99%;METHYL 3-HYDROXY-4-METHOXYPHENYLACETATE(WXG02285)
• CAS NO: 15964-81-5
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.19988
• Mol File: 15964-81-5.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 131℃/1mm
• Appearance: /
• Density: 1.191±0.06 g/cm3(Predicted)
• PKA: 9.65±0.12(Predicted)
• CAS DataBase Reference: Methyl 3-hydroxy-4-methoxyphenylacetate, 99%(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-hydroxy-4-methoxyphenylacetate, 99%(15964-81-5)
• EPA Substance Registry System: Methyl 3-hydroxy-4-methoxyphenylacetate, 99%(15964-81-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 15964-81-5(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 89936-29-8 2-(3,5-dibromo-4-methoxyphenyl)acetic acid 
• 1131-94-8 homoisovanillic acid 
• 104-01-8 4-Methoxyphenylacetic acid 
• 23786-14-3 4-methoxy-phenyl acetic acid methyl ester 

Downstream Products

• 857556-44-6 [3-(4-formyl-2-methoxy-6-nitro-phenoxy)-4-methoxy-phenyl]-acetic acid methyl ester 
• 50602-41-0 3-hydroxy-4-methoxyphenethyl alcohol 
• 133332-37-3 methyl 2-(3-cyclopentoxy-4-methoxyphenyl)ethanoate 
• 828252-27-3 (4-methoxy-3-trifluoromethanesulfonyloxy-phenyl)-acetic acid methyl ester 
• 959972-25-9 [4-methoxy-3-(2-methoxyethoxy)phenyl]acetic acid methyl ester 
• 562840-55-5 3-formyl-4-methoxyphenylacetic acid methyl ester 
• 828252-28-4 (3-cyano-4-methoxy-phenyl)-acetic acid methyl ester 
• 927187-51-7 (3-{4-[2-(2,4-dichloro-phenoxy)-ethylcarbamoyl]-5-phenyl-isoxazol-3-yl}-4-methoxy-phenyl)-acetic acid methyl ester 
• 141333-59-7 2-(3-cyclopentyloxy-4-methoxyphenyl)acetic acid 
• 203441-50-3 2-(3-Cyclopentyloxy-4-methoxy-phenyl)-indan-1,3-dione 
• 203441-51-4 5-Benzyloxy-2-(3-cyclopentyloxy-4-methoxy-phenyl)-indan-1,3-dione 
• 203439-54-7 2-(3-Cyclopentyloxy-4-methoxy-phenyl)-2-pyridin-4-ylmethyl-indan-1,3-dione 
• 203440-63-5 2-(3-Cyclopentyloxy-4-methoxy-phenyl)-5-hydroxy-2-pyridin-4-ylmethyl-indan-1,3-dione 
• 203439-58-1 Acetic acid 4-[2-(3-cyclopentyloxy-4-methoxy-phenyl)-1,3-dioxo-indan-2-ylmethyl]-phenyl ester 

Relevant articles and documents

Phenol nitration from a 2-(nitrooxy)ethyl side chain

A novel nitration of phenols is described on 2-(3-hydroxy-4-methoxyphenyl)ethyl nitrate (2), which is synthesized by three alternative routes.

Total synthesis of three natural phenethyl glycosides

Phenethyl glycosides having phenolic or methoxy functions at benzene rings are substances widely occurring in nature. This kind of compounds has been shown to have anti-oxidant, anti-inflammatory, and anticancer activities. However, some of them are not naturally abundant, thus the synthesis of such molecules is desirable. In this paper, natural phenethyl glycosides 3 and 4 were first totally synthesized from easily available materials with overall yields of 50.5% and 40.1%, respectively. And a new synthetic route to obtain natural phenethyl glycoside 2 in 46.2% yield was also described.

CYCLIC PEROXIDE OXIDATION OF AROMATIC COMPOUND PRODUCTION AND USE THEREOF

The present invention provides a method for converting an aromatic hydrocarbon to a phenol by providing an aromatic hydrocarbon comprising one or more aromatic C-H bonds and one or more activated C-H bonds in a solvent; adding a phthaloyl peroxide to the solvent; converting the phthaloyl peroxide to a di-radical; contacting the di-radical with the one or more aromatic C-H bonds; oxidizing selectively one of the one or more aromatic C-H bonds in preference to the one or more activated C-H bonds; adding a hydroxyl group to the one of the one or more aromatic C-H bonds to form one or more phenols; and purifying the one or more phenols.