562840-55-5

Basic information

• Product Name: 3-formyl-4-methoxyphenylacetic acid methyl ester
• CAS NO: 562840-55-5
• Molecular Weight: 208.214
• Mol File: 562840-55-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-formyl-4-methoxyphenylacetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-formyl-4-methoxyphenylacetic acid methyl ester(562840-55-5)
• EPA Substance Registry System: 3-formyl-4-methoxyphenylacetic acid methyl ester(562840-55-5)

Safety Data

• Hazardous Substances Data: 562840-55-5(Hazardous Substances Data)

Upstream product

• 15964-81-5 methyl 3-hydroxy-4-methoxyphenylacetate 
• 1131-94-8 homoisovanillic acid 
• 828252-27-3 (4-methoxy-3-trifluoromethanesulfonyloxy-phenyl)-acetic acid methyl ester 
• 828252-28-4 (3-cyano-4-methoxy-phenyl)-acetic acid methyl ester 

Downstream Products

• 927187-51-7 (3-{4-[2-(2,4-dichloro-phenoxy)-ethylcarbamoyl]-5-phenyl-isoxazol-3-yl}-4-methoxy-phenyl)-acetic acid methyl ester 

Relevant articles and documents

3,4,5-Trisubstituted isoxazoles as novel PPARδ agonists. Part 2

A series of PPARδ-selective agonists was investigated and optimized for a favorable in vivo pharmacokinetic profile. Isoxazole LCI765 (17d) was found to be a potent and selective PPARδ agonist with good in vivo PK properties in mouse (Cmax = 5.1 μM, t1/2 = 3.1 h). LCI765 regulated expression of genes involved in energy homeostasis in relevant tissues when dosed orally in C57BL6 mice. A co-crystal structure of compound LCI765 and the LBD of PPARδ is discussed.