160516-03-0Relevant articles and documents
DIKETO ACIDS WITH NUCLEOBASE SCAFFOLDS: ANTI-HIV REPLICATION INHIBITORS TARGETED AT HIV INTEGRASE IN COMBINATION THERAPY
-
, (2008/06/13)
A new class of diketo acids constructed on nucleobase scaffolds, designed as inhibitors of HIV replication through inhibition of HIV integrase, is described. These compounds are useful in the prevention or treatment of infection by HFV and in the treatmen
Diketo acids with nucleobase scaffolds: anti-HIV replication inhibitors targeted at HIV integrase
-
Page/Page column 19-20, (2008/06/13)
A new class of diketo acids constructed on nucleobase scaffolds, designed as inhibitors of HIV replication through inhibition of HIV integrase, is described. These compounds are useful in the prevention or treatment of infection by HIV and in the treatmen
6-Halopurines in palladium-catalyzed coupling with organotin and organozinc reagents
Gundersen,Bakkestuen,Aasen,Overas,Rise
, p. 9743 - 9756 (2007/10/02)
N-9 and N-7 benzylated 6-halopurines readily participate in palladium catalyzed cross coupling reactions with organotin and organozinc derivatives. In most instances the 6-chloropurines can be used. Organostannanes are excellent reagents for the introduction of alkenyl and aryl substituents, but organozinc compounds are the reagents of choice for the introduction of alkyl groups.