1606141-48-3Relevant articles and documents
Thermally induced substrate release via intramolecular cyclizations of Amino esters and Amino carbonates
Knipp, Ralph J.,Estrada, Rosendo,Sethu, Palaniappan,Nantz, Michael H.
, p. 3422 - 3429 (2014)
The relative cleavage of an alcohol from a panel of amino esters and amino carbonates via intramolecular cyclization was examined as a mechanism for substrate release. Thermal stability at 37 °C was observed only for the seven-membered ring progenitors. Applicability of the approach was illustrated by δ-lactam formation within a poly(dimethylsiloxane) microchannel for release of a captured fluorescent probe.