1606142-51-1Relevant articles and documents
Efficient and eco-friendly syntheses of 1,5-benzothiazepines and 1,5-benzodiazepines catalyzed by [Hmim][NO3] under mild conditions
Loghmani-Khouzani, Hossein,Tamjidi, Panteha,Mohammadpoor-Baltork, Iraj,Yaeghoobi, Marzieh,Rahman, Noorsaadah Abd.,Khosropour, Ahmad Reza,Moghadam, Majid,Tangestaninejad, Shahram,Mirkhani, Valiolah,Habibi, Mohammad Hossein,Kashima, Ayana,Suzuki, Takayoshi
, p. 138 - 150 (2014/02/14)
This article presents a synthetic method and reaction mechanism of the 1,5-benzothiazepines and 1,5-benzodiazepines derivatives. In this research, 36 thiazepines and diazepines (mostly new) with a new method have been prepared and their structures have been characterized by spectroscopic methods. Crystal structures of a new thiazepine and diazepine (seven-membered rings) have also been determined and compared with thiazine (six-membered ring). In this method, N-methylimidazolium nitrate [Hmim][NO3] has been used as a catalyst that acts as an environmental friendly system.