1610527-49-5 Usage
Description
(2,4-diMethylphenyl)(2-nitrophenyl)sulfane is an organic compound that plays a significant role in the pharmaceutical industry, particularly in the synthesis and purification of drug substances. It is characterized by its unique chemical structure, which includes a sulfur atom bonded to two different aromatic rings, one being a 2,4-dimethylphenyl group and the other a 2-nitrophenyl group.
Uses
Used in Pharmaceutical Industry:
(2,4-diMethylphenyl)(2-nitrophenyl)sulfane is used as a reactant for studying the generic industry approach to efficient purification of potential mutagenic impurities in the synthesis of drug substances. Its application is crucial in ensuring the safety and quality of the final drug products by minimizing the presence of harmful impurities that could pose health risks to patients.
In the context of drug synthesis, (2,4-diMethylphenyl)(2-nitrophenyl)sulfane aids in the development of processes that can effectively separate and remove mutagenic impurities, which are byproducts formed during the chemical reactions involved in drug production. By employing this compound as a reactant, researchers and pharmaceutical companies can optimize their purification techniques, leading to the production of drugs with higher purity and fewer potential side effects.
Furthermore, the use of (2,4-diMethylphenyl)(2-nitrophenyl)sulfane in the pharmaceutical industry also contributes to the overall improvement of drug manufacturing processes. By focusing on the efficient purification of mutagenic impurities, this compound helps to enhance the overall quality and safety of drug substances, ultimately benefiting patients and the healthcare sector as a whole.
Check Digit Verification of cas no
The CAS Registry Mumber 1610527-49-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,1,0,5,2 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1610527-49:
(9*1)+(8*6)+(7*1)+(6*0)+(5*5)+(4*2)+(3*7)+(2*4)+(1*9)=135
135 % 10 = 5
So 1610527-49-5 is a valid CAS Registry Number.
1610527-49-5Relevant articles and documents
Chemoselective Hydrogenation of Nitroarenes Using an Air-Stable Base-Metal Catalyst
Zubar, Viktoriia,Dewanji, Abhishek,Rueping, Magnus
supporting information, p. 2742 - 2747 (2021/05/05)
The reduction of nitroarenes to anilines as well as azobenzenes to hydrazobenzenes using a single base-metal catalyst is reported. The hydrogenation reactions are performed with an air-and moisture-stable manganese catalyst and proceed under relatively mild reaction conditions. The transformation tolerates a broad range of functional groups, affording aniline derivatives and hydrazobenzenes in high yields. Mechanistic studies suggest that the reaction proceeds via a bifunctional activation involving metal-ligand cooperative catalysis.
Metal-Free Cercosporin-Photocatalyzed C-S Coupling for the Selective Synthesis of Aryl Sulfides under Mild Conditions
Li, Jia,Bao, Wenhao,Zhang, Yan,Rao, Yijian
supporting information, p. 7175 - 7178 (2019/11/16)
Aryl sulfides are important motifs of bioactive molecules, which are generally synthesized by transition metal-based coupling reactions under harsh conditions. Herein, we developed a new method that visible light along with cercosporin, produced by liquid fermentation and functioned as a cost-effective and environmentally friendly photocatalyst, prompted the selective synthesis of aryl sulfides through C–S coupling of thiols and diazonium salts under mild conditions. Furthermore, this method can also be performed with a great conversion by the direct use of cercosporin-containing fermentation supernatant as catalytic system without organic solvent extraction.
1-[2-(2,4-dimethylphenylsulfydryl)phenyl]piperazine hydrochloride and preparation method thereof
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Paragraph 0019; 0020, (2018/04/28)
The invention discloses 1-[2-(2,4-dimethylphenylsulfydryl)phenyl]piperazine hydrochloride and a preparation method thereof. By means of the specific preparation method, the HPLC purity of vortioxetinehydrochloride is higher than 99.5%, and the content of
