1611466-21-7Relevant articles and documents
Stereocontrol by quaternary centres: A stereoselective synthesis of (-)-luminacin D
Bartlett, Nathan,Gross, Leona,Peron, Florent,Asby, Daniel J.,Selby, Matthew D.,Tavassoli, Ali,Linclau, Bruno
, p. 3306 - 3310 (2014/04/03)
Very high diastereoselectivity can be achieved by 1,3-chelation-controlled allylation of aldehydes that possess a non-chelating α-ether substituent, even if the α-position is a quaternary centre and/or a spiro-epoxide. This reaction was used as a key step in an enantioselective synthesis of the angiogenesis inhibitor luminacin D.