1613024-18-2

Basic information

• Product Name: 3-(((4-fluorophenyl)sulfonyl)methyl)-1,3-dimethylindolin-2-one
• Synonyms: 3-(((4-fluorophenyl)sulfonyl)methyl)-1,3-dimethylindolin-2-one
• CAS NO: 1613024-18-2
• Molecular Weight: 333.383
• Mol File: 1613024-18-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-(((4-fluorophenyl)sulfonyl)methyl)-1,3-dimethylindolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(((4-fluorophenyl)sulfonyl)methyl)-1,3-dimethylindolin-2-one(1613024-18-2)
• EPA Substance Registry System: 3-(((4-fluorophenyl)sulfonyl)methyl)-1,3-dimethylindolin-2-one(1613024-18-2)

Safety Data

• Hazardous Substances Data: 1613024-18-2(Hazardous Substances Data)

Upstream product

• 732306-64-8 bis(4-fluorophenyl)iodonium triflate 
• 15796-89-1 N-methyl-N-phenylmethacrylamide 
• 100-61-8 N-methylaniline 
• 369-51-7 4-fluorobenzenesulfinic acid 
• 824-80-6 sodium 4-fluorobenzenesulfinate 
• 349-88-2 4-Fluorobenzenesulfonyl chloride 

Relevant articles and documents

Hydrogen and Sulfonyl Radical Generation for the Hydrogenation and Arylsulfonylation of Alkenes Driven by Photochemical Activity of Hydrogen Bond Donor-Acceptor Complexes

An efficient photoinduced strategy for the hydrogenation and arylsulfonylation of alkenes has been developed. The reaction afforded a range of hydrogenated products and sulfonated oxindoles in high yields under external photocatalyst-free, oxidant- and reductant-free conditions. Mechanistic investigations suggested this transformation is driven by the photochemical activity of hydrogen bond donor-acceptor complex, generated from the substrates of arylsulfinic acids and C6-(vinyl sulfone)phenanthridines or N-arylacrylamides via hydrogen bond interaction. (Figure presented.).

Visible-Light Photoredox Catalysis: Direct Synthesis of Sulfonated Oxindoles from N-Arylacrylamides and Arylsulfinic Acids by Means of a Cascade C-S/C-C Formation Process

A novel photocatalytic synthesis of sulfonated oxindoles from N-arylacrylamides and arylsulfinic acids was developed by means of a cascade C-S/C-C bond-formation process. This method provides mild, efficient, and atom-economical access to various sulfonated oxindoles in water. Let there be light! A novel photocatalytic synthesis of sulfonated oxindoles from N-arylacrylamides and arylsulfinic acids was developed by means of a cascade C-S/C-C bond-formation process. This method provides mild, efficient, and atom-economical access to various sulfonated oxindoles in water (see scheme).

Synthesis of oxindoles through silver-catalyzed trifluoromethylation-, difluoromethylation- and arylsulfonylation-cyclization reaction of N-arylacrylamides

Efficient synthesis of trifluoromethyl and difluoromethyl-substituted oxindoles was achieved by reacting Langlois reagent or Baran reagent with N-arylacrylamides. However, the reaction of aryl sulfinic acid sodium salts with N-arylacrylamides did not give the desulfinative products, instead, aryl sulfonated products were produced. Copyright