1616890-19-7

Basic information

• Product Name: 2-[4-(dimethylamino)phenyl]-4-oxo-4-p-tolylbutanenitrile
• Synonyms: 2-[4-(dimethylamino)phenyl]-4-oxo-4-p-tolylbutanenitrile
• CAS NO: 1616890-19-7
• Molecular Weight: 292.381
• Mol File: 1616890-19-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[4-(dimethylamino)phenyl]-4-oxo-4-p-tolylbutanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(dimethylamino)phenyl]-4-oxo-4-p-tolylbutanenitrile(1616890-19-7)
• EPA Substance Registry System: 2-[4-(dimethylamino)phenyl]-4-oxo-4-p-tolylbutanenitrile(1616890-19-7)

Safety Data

• Hazardous Substances Data: 1616890-19-7(Hazardous Substances Data)

Upstream product

• 19132-98-0 3-[4-(dimethylamino)phenyl]-1-(4-methylphenyl)prop-2-en-1-one 
• 109-77-3 malononitrile 

Relevant articles and documents

Synthesis of β-cyanopropan-1-one derivates by domino reaction

Domino nucleophilic addition was used for four-component Al 2O3-catalyzed environmentally friendly synthesis of polysubstituted β-cyanopropan-1-one. Domino nucleophilic addition involves removal of the cyano group linked to active methylene by the action of KF, and direct addition to enones. The reaction's capability for nucleophilic attack is F- > CN- in DMF. The use of low-toxicity reagents hints that the reaction is more environmentally friendly than traditional approaches. This journal is the Partner Organisations 2014.