161711-27-9 Usage
Description
(1R,2R)-2-(4-fluorophenyl)cyclopropanecarboxylic acid is a chiral chemical compound with the molecular formula C11H11FO2. It belongs to the class of cyclopropane carboxylic acids and features a cyclopropane ring fused with a fluorophenyl group. The presence of a stereocenter at the cyclopropane carbon endows this compound with unique structural and functional properties. Its distinctive features make it a promising candidate for applications in pharmaceuticals and agrochemicals, warranting further research and development.
Uses
Used in Pharmaceutical Industry:
(1R,2R)-2-(4-fluorophenyl)cyclopropanecarboxylic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications, particularly in the treatment of diseases that require chiral molecules for their action.
Used in Agrochemical Industry:
In the agrochemical field, (1R,2R)-2-(4-fluorophenyl)cyclopropanecarboxylic acid is utilized as a building block for the creation of novel agrochemicals. Its specific stereochemistry and chemical properties can be harnessed to develop new pesticides, herbicides, or insecticides that are more effective, selective, and environmentally friendly.
Used in Research and Development:
(1R,2R)-2-(4-fluorophenyl)cyclopropanecarboxylic acid serves as an important compound for research purposes. Its synthesis and properties are of interest to chemists and biologists who aim to understand its behavior in various chemical reactions and biological systems. This knowledge can lead to the discovery of new applications and improvements in existing ones.
Check Digit Verification of cas no
The CAS Registry Mumber 161711-27-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,7,1 and 1 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 161711-27:
(8*1)+(7*6)+(6*1)+(5*7)+(4*1)+(3*1)+(2*2)+(1*7)=109
109 % 10 = 9
So 161711-27-9 is a valid CAS Registry Number.
161711-27-9Relevant articles and documents
KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE
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Paragraph 0270, (2014/10/18)
Disclosed herein are new compounds and compositions and their application as pharmaceuticals for the treatment of diseases. Methods of inhibition of KDMIA, and methods of increasing gamma globin gene expression in a human or animal subject are also provided for the treatment diseases such as sickle cell disease.
Enantioselective synthesis of tranylcypromine analogues as lysine demethylase (LSD1) inhibitors
Benelkebir, Hanae,Hodgkinson, Christopher,Duriez, Patrick J.,Hayden, Annette L.,Bulleid, Rosemary A.,Crabb, Simon J.,Packham, Graham,Ganesan
experimental part, p. 3709 - 3716 (2011/08/02)
Asymmetric cyclopropanation of styrenes by tert-butyl diazoacetate followed by ester hydrolysis and Curtius rearrangement gave a series of tranylcypromine analogues as single enantiomers. The o,- m- and p-bromo analogues were all more active than tranylcypromine in a LSD1 enzyme assay. The m- and p-bromo analogues were micromolar growth inhibitors of the LNCaP prostate cancer cell line as were the corresponding biphenyl analogues prepared from the bromide by Suzuki crosscoupling.
Triazolo(4,5-d)pyrimidine compounds
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Example 34, (2010/11/29)
Triazolo[4,5-d]pyrimidine compounds are provided of the formula (I) wherein R1, R2, R3, R4, R5and R6are as defined in the specification. Compositions containing the compounds are also provided, together with processes for their preparation and methods of use in the treatment of diseases, including myocardial infarction and unstable angina.
