161891-80-1

Basic information

• Product Name: 4-Thiazolecarboxylicacid,2-(1-hydroxyethyl)-,ethylester(9CI)
• Synonyms: 4-Thiazolecarboxylicacid,2-(1-hydroxyethyl)-,ethylester(9CI)
• CAS NO: 161891-80-1
• Molecular Formula: C₈H₁₁NO₃S
• Molecular Weight: 201.24
• Product Categories: THIAZOLE
• Mol File: 161891-80-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 297.1±20.0 °C(Predicted)
• Appearance: /
• Density: 1.276±0.06 g/cm3(Predicted)
• PKA: 12.91±0.20(Predicted)
• CAS DataBase Reference: 4-Thiazolecarboxylicacid,2-(1-hydroxyethyl)-,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Thiazolecarboxylicacid,2-(1-hydroxyethyl)-,ethylester(9CI)(161891-80-1)
• EPA Substance Registry System: 4-Thiazolecarboxylicacid,2-(1-hydroxyethyl)-,ethylester(9CI)(161891-80-1)

Safety Data

• Hazardous Substances Data: 161891-80-1(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 76275-85-9 ethyl 2-<1-(benzoyloxy)ethyl>thiazole-4-carboxylate 
• 73956-16-8 ethyl 2-(diethoxymethyl)-1,3-thiazole-4-carboxylate 
• 73956-17-9 ethyl 2-formyl-1,3-thiazole-4-carboxylate 
• 75-16-1 methylmagnesium bromide 
• 1372541-86-0 ethyl 2-(diethoxymethyl)-2-thiazoline-4-carboxylate 
• 3411-58-3 L-cysteine ethylester 

Downstream Products

• 160060-21-9 2-acetylthiazol-4-carboxylic acid ethyl ester 
• 13139-47-4 2-acetylthiazole-4-carboxylic acid 

Relevant articles and documents

Easy access to 2-alkyl and 2-arylthiazolines using a modified heteropolyacid catalysis: Application to the synthesis of bacillamide A

A straightforward access to 2-alkyl and 2-arylthiazolines by condensation of-aminothiols on nitriles, catalyzed by phosphotungstic acid (2%) under microwave irradiation, is described. This method has been directly applied to a short and efficient synthesi

Synthesis of ozonolysis products of myxothiazol

By applying the Hantzsch thiazole procedure, the synthesis of bithiazole derivatives (2 and (±)-3) corresponding to degradation products of myxothiazol was achieved. Optically active (S)-3 (87-88% ee) and its analog (S)-16 (91% ee) were obtained through enantioselective hydrolysis of the corresponding acetates ((±)-18, (±)-20 and (±)-21) using lipase in water- saturated organic solvent.