1621065-09-5

Basic information

• Product Name: 1-((4-methyl-2-((cis-4-(trimethylsilyl)cyclohexyl)oxy)naphthalen-1-yl)methyl)piperidine-4-carboxylic acid
• Synonyms: 1-((4-methyl-2-((cis-4-(trimethylsilyl)cyclohexyl)oxy)naphthalen-1-yl)methyl)piperidine-4-carboxylic acid
• CAS NO: 1621065-09-5
• Molecular Weight: 453.697
• Mol File: 1621065-09-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-((4-methyl-2-((cis-4-(trimethylsilyl)cyclohexyl)oxy)naphthalen-1-yl)methyl)piperidine-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-((4-methyl-2-((cis-4-(trimethylsilyl)cyclohexyl)oxy)naphthalen-1-yl)methyl)piperidine-4-carboxylic acid(1621065-09-5)
• EPA Substance Registry System: 1-((4-methyl-2-((cis-4-(trimethylsilyl)cyclohexyl)oxy)naphthalen-1-yl)methyl)piperidine-4-carboxylic acid(1621065-09-5)

Safety Data

• Hazardous Substances Data: 1621065-09-5(Hazardous Substances Data)

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 877-68-9 4-trimethylsilylanisole 
• 1621065-10-8 ethyl 1-((4-methyl-2-((cis-4-(trimethylsilyl)cyclohexyl)oxy)naphthalen-1-yl)methyl)piperidine-4-carboxylate 
• 7452-94-0 (trans)-4-(trimethylsilyl)cyclohexanol 
• 7452-95-1 4-trimethylsilylcyclohexan-1-one 

Relevant articles and documents

S1P MODULATING AGENTS

Compounds of formula (I) can modulate the activity of one or more S 1P receptors. Sphingosine 1-phosphate (S IP) is a lysophospholipid mediator that evokes a variety of cellular responses by stimulation of five members of the endothelial cell differentiation gene (EDG) receptor family, namely S1P1, S1P2, S1P3, S1P4, and S1P5 (formerly EDG1, EDG5, EDG3, EDG6 and EDG8). The EDG receptors are G-protein coupled receptors (GPCRs) and on stimulation propagate second messenger signals via activation of heterotrimeric G-protein alpha (Ga.) subunits and beta-gamma (G()y) dimers.