1621165-11-4

Basic information

• Product Name: tert-butyl 4-bromo-2,5-difluorobenzoate
• Synonyms: tert-butyl 4-bromo-2,5-difluorobenzoate
• CAS NO: 1621165-11-4
• Molecular Weight: 293.108
• Mol File: 1621165-11-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-bromo-2,5-difluorobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-bromo-2,5-difluorobenzoate(1621165-11-4)
• EPA Substance Registry System: tert-butyl 4-bromo-2,5-difluorobenzoate(1621165-11-4)

Safety Data

• Hazardous Substances Data: 1621165-11-4(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 28314-82-1 4-bromo-2,5-difluorobenzoic acid 
• 327-51-5 1,4-dibromo-2,5-difluorobenzene 

Downstream Products

• 1621165-14-7 2,5-difluoro-4-formyl-N-methylbenzamide 
• 28314-82-1 4-bromo-2,5-difluorobenzoic acid 
• 1621165-12-5 4-bromo-2,5-difluoro-N-methylbenzamide 
• 1621165-13-6 4-cyano-2,5-difluoro-N-methylbenzamide 

Relevant articles and documents

5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL DERIVATIVES FOR THE TREATMENT OF CANCER

The present invention provides Compound (I), 2-butoxy-N-(2-chloro-6-fluorophenyl)-4-[3-(2-chlorophenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-5-fluorobenzamide and Compound (II), N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-5-fluoro-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}benzamide, (II): and stereoisomers, tautomers, N-oxides, hydrates, solvates, and salts thereof, and mixtures of same, methods for the preparation of Compound (I) and Compound (II) and their use for the treatment of hyperproliferative diseases, particularly cancer.