16227-22-8

Basic information

• Product Name: glycyl-L-phenylalanine methyl ester
• CAS NO: 16227-22-8
• Molecular Weight: 236.271
• Mol File: 16227-22-8.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: glycyl-L-phenylalanine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: glycyl-L-phenylalanine methyl ester(16227-22-8)
• EPA Substance Registry System: glycyl-L-phenylalanine methyl ester(16227-22-8)

Safety Data

• Hazardous Substances Data: 16227-22-8(Hazardous Substances Data)

Upstream product

• 129397-81-5 methyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-phenylalaninate 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 106624-70-8 methyl (2S)-2-[[2-(t-butoxycarbonylamino)acetyl]amino]-3-phenylpropanoate 
• 6206-42-4 N-benzyloxycarbonylglycyl-L-phenylalanine methyl ester 
• 56-40-6 glycine 
• 6913-23-1 2-thioxo-thiazolidin-5-one 
• 15028-44-1 DL-phenylalanine methyl ester 
• 811-98-3 d⁽⁴⁾-methanol 

Downstream Products

• 114479-32-2 (S)-2-(2-Isobutoxycarbonylamino-acetylamino)-3-phenyl-propionic acid methyl ester 
• 114479-31-1 Boc-D-Met-Gly-Phe-OMe 
• 114479-31-1 Boc-L-Met-Gly-Phe-OMe 
• 87242-56-6 Ac-ΔTyr(Ac)-(R)-Ala-Gly-(S)-Phe-OMe 
• 142929-43-9 N--3-<(triphenylmethyl)thio>-D-valyl>glycyl>-L-phenylalanine methyl ester 
• 1393661-62-5 C₂₉H₂₉N₃O₆ 
• 159789-40-9 C₃₈H₃₈N₄O₈ 
• 1393661-63-6 C₃₇H₃₈N₆O₇ 
• 1393661-64-7 C₅₆H₅₇N₇O₁₀ 
• 1393661-65-8 C₅₇H₅₉N₇O₁₀ 
• 71921-20-5 methyl glycylglycyl-L-phenylalaninate 
• 902493-50-9 (S)-methyl 2-(2-isocyanoacetamido)-3-phenylpropanoate 

Relevant articles and documents

Synthesis and Characterization of a Series of Orthogonally Protected l-Carnosine Derivatives

l-Carnosine (β-alanyl-l-histidine) is an endogenous dipeptide that has been recognized for its broad spectrum of beneficial biological activities. However, the therapeutic utility of molecule has been hampered by its instability in human plasma (half-life

"Backdoor Induction" of chirality in asymmetric hydrogenation with rhodium(I) complexes of amino acid substituted triphenylphosphane ligands

This paper describes the synthesis and characterization of 5-(diphenylphosphanyl)isophthalic acid bioconjugates (Lig-[R]2). In addition to symmetrically disubstituted conjugates with amino acids, peptides or amines, a convenient one-pot, two-step procedure for the synthesis of conjugates bearing two different substituents is reported. The 28 prepared phosphanes were used as monodentate ligands in the rhodium(I)-catalyzed hydrogenation of 2-acetamidoacrylate and (Z)-α-acetamidocinnamate. The ligand with the smallest side-chain substituents Lig-[Ala-OMe]2 (1a) revealed the highest selectivity, with up to 84 % ee. The catalysts presented herein are models of artificial metalloenzymes in which the outer-coordination sphere controls the selectivity in catalysis. The chirality of distant hydrogen-bonded amino acids is transmitted by "backdoor induction" to the prochiral RhI center. Models of artificial metalloenzymes are presented in which the outer-coordination sphere controls the selectivity in catalysis. The chirality of distant hydrogen-bonded amino acids or amines is transmitted by "backdoor induction" to the prochiral RhI center. Copyright

Synthesis of Sansalvamide A derivatives and their cytotoxicity in the MSS colon cancer cell line HT-29

We report the synthesis of thirty-six Sansalvamide A derivatives, and their biological activity against colon cancer HT-29 cell line, a microsatellite stable (MSS) colon cancer cell-line. The thirty-six compounds can be divided into three subsets, where t