164025-07-4Relevant articles and documents
Photochemical Reaction of N,N-Dimethylanilines with N-Substituted Maleimides Utilizing Benzaldehyde as the Photoinitiator
Nikitas, Nikolaos F.,Theodoropoulou, Maria A.,Kokotos, Christoforos G.
supporting information, p. 1168 - 1173 (2021/02/01)
Photoorganocatalysis constitutes a powerful domain of photochemistry and organic synthesis. The scaffold of pyrrolo[3,4-c]quinolinoles exhibits interesting and potent inhibition against various enzymes, making them really promising pharmaceutical targets. Herein, we describe a photochemical methodology for the reaction of N,N-dimethylanilines with N-substituted maleimides, utilizing benzaldehyde as the photoinitiator. A variety of substituted N,N-dimethylanilines and N-substituted maleimides were converted into the corresponding adducts in moderate to high yields.
Structure-reactivity relationships in a recognition mediated [3+2] dipolar cycloaddition reaction
Sinclair, Andrew J.,Del Amo, Vicente,Philp, Douglas
supporting information; experimental part, p. 3308 - 3318 (2009/10/23)
The [3+2] dipolar cycloaddition between an azide and maleimide can be accelerated by a factor of more than 100 simply by attaching complementary recognition sites to the reactive partners. This rate acceleration derives from the formation of a reactive bi
Luminescent crown ether amino acids: Selective binding to N-terminal lysine in peptides
Mandl, Christian P.,Koenig, Burkhard
, p. 670 - 674 (2007/10/03)
(Chemical Equation Presented) Crown ether amino acids (CEAAs) with a luminescent phthalic ester or phthalimide moiety have been prepared. Simple peptide chemistry covalently tethers the macrocycles to give ditopic ammonium-ion binders. The binding events