16503-47-2

Basic information

• Product Name: BENZENEBUTANOIC ACID,A-BROMO-,METHYL ESTER
• Synonyms: BENZENEBUTANOIC ACID,A-BROMO-,METHYL ESTER;Methyl 2-broMo-4-phenylbutanoate;BENZENEBUTANOIC ACID,α-BROMO-,METHYL ESTER;Benzenebutanoic acid, alpha-bromo-, methyl ester
• CAS NO: 16503-47-2
• Molecular Formula: C₁₁H₁₃BrO₂
• Molecular Weight: 257.13
• Mol File: 16503-47-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 298.4±28.0 °C(Predicted)
• Appearance: /
• Density: 1.361±0.06 g/cm3(Predicted)
• CAS DataBase Reference: BENZENEBUTANOIC ACID,A-BROMO-,METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: BENZENEBUTANOIC ACID,A-BROMO-,METHYL ESTER(16503-47-2)
• EPA Substance Registry System: BENZENEBUTANOIC ACID,A-BROMO-,METHYL ESTER(16503-47-2)

Safety Data

• Hazardous Substances Data: 16503-47-2(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 292638-85-8 acrylic acid methyl ester 
• 67-56-1 methanol 
• 84299-48-9 2-bromo-4-phenyl-butyryl chloride 
• 18496-54-3 phenylbutyric acid chloride 
• 1821-12-1 4-Phenylbutyric acid 

Downstream Products

• 131786-79-3 2-phenyl-4-hydroxy-5-phenethylthiazole 
• 185298-40-2 2-(1-Benzyl-2-ethyl-1H-indol-4-yloxy)-4-phenyl-butyric acid methyl ester 
• 185298-54-8 2-(3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-4-phenyl-butyric acid methyl ester 
• 902146-90-1 methyl 2-(4-butyl-2,3-dioxopiperazin-1-yl)-4-phenylbutanoate 

Relevant articles and documents

AMINOMETHYL BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention is directed to aminomethyl compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is als

HOMOLYTIC ADDITION OF BENZYL BROMIDE TO UNSATURATED COMPOUNDS IN CONDITIONS OF METAL-COMPLEX INITIATION

Radical addition of benzyl bromide to unsaturated compounds containing substituents of a different polar nature, CH2=CHX (X = C4H9, SiMe3, CF3, CO2Me, CN, H), was conducted in the presence of the Fe(CO)5 + DMF (HMPA) system.Adducts were obtained and their structure was demonstrated by 13C NMR and mass spectrometry.Keywords: homolytic addition, benzyl bromide, unsaturated compounds, iron pentacarbonyl, DMF, HMPA.