16537-16-9

Basic information

• Product Name: Benzoic acid, 2-chloro-, 1,1-dimethylethyl ester
• CAS NO: 16537-16-9
• Molecular Formula: C11H13ClO2
• Molecular Weight: 212.676
• Mol File: 16537-16-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-chloro-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-chloro-, 1,1-dimethylethyl ester(16537-16-9)
• EPA Substance Registry System: Benzoic acid, 2-chloro-, 1,1-dimethylethyl ester(16537-16-9)

Safety Data

• Hazardous Substances Data: 16537-16-9(Hazardous Substances Data)

Upstream product

• 870195-94-1 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-chlorobenzene 
• 24424-99-5 di-tert-butyl dicarbonate 
• 3900-89-8 2-Chlorobenzeneboronic acid 
• 75-91-2 tert.-butylhydroperoxide 
• 2856-63-5 2-Chlorophenylacetonitrile 
• 1634-04-4 tert-butyl methyl ether 
• 118-91-2 ortho-chlorobenzoic acid 
• 609-65-4 o-chlorobenzoyl chloride 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 118-91-2 ortho-chlorobenzoic acid 
• 70132-79-5 (2-chlorophenyl)(2,5-dimethylphenyl)methanone 

Relevant articles and documents

Silver/manganese dioxide nanorod catalyzed hydrogen-borrowing reactions and tert-butyl ester synthesis

Silver/manganese dioxide (Ag@MnO2) nanorods are synthesized and characterized by scanning electron microscopy, transmission electron microscopy, energy dispersive X-ray spectroscopy, X-ray powder diffraction, and X-ray photoelectron spectroscopy. It was discovered that Ag@MnO2 nanorods can realize hydrogen-borrowing reactions in high yields and are also effective for the synthesis of tert-butyl esters from aryl cyanides and tert-butyl hydroperoxide in a short period of time. Mechanistic experiments revealed that this catalytic system acts as a Lewis acid in hydrogen-borrowing reactions, while the synthesis of tert-butyl esters occurs through a radical pathway. This is the first report on the excellent catalytic activity of Ag@MnO2 nanorods as a catalyst.

A mesoporous organosilica grafted Pd catalyst (MOG-Pd) for efficient base free and phosphine free synthesis of tertiary butyl esters via tertiary-butoxycarbonylation of boronic acid derivatives without using carbon monoxide

A mesoporous organosilica grafted palladium(ii) catalyst was synthesized and characterized using various spectroscopic techniques. Its catalytic activity was evaluated for the synthesis of tertiary butyl esters via tert-butoxycarbonylation of boronic acid

One-pot esterification and Ritter reaction: Chemo- and regioselectivity from tert-butyl methyl ether

tert-Butyl methyl ether (TBME) has been effectively used as a reagent for esterification of carboxylic acids. By varying amounts of sulfuric acid, a remarkable regioselectivity in esterification has been demonstrated. Additionally, under the present reaction conditions, one-pot esterification and Ritter reaction are achieved in almost quantitative yield.