165528-85-8

Basic information

• Product Name: 1-Boc-4-(3-oxopropyl)piperidine
• Synonyms: 1-Boc-4-(3-oxopropyl)piperidine;tert-butyl 4-(3-oxopropyl)piperidine-1-carboxylate
• CAS NO: 165528-85-8
• Molecular Formula: C₁₃H₂₃NO₃
• Molecular Weight: 241.33
• Product Categories: pharmacetical
• Mol File: 165528-85-8.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 334.0±15.0 °C(Predicted)
• Appearance: /
• Density: 1.022±0.06 g/cm3(Predicted)
• PKA: -1.41±0.40(Predicted)
• CAS DataBase Reference: 1-Boc-4-(3-oxopropyl)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Boc-4-(3-oxopropyl)piperidine(165528-85-8)
• EPA Substance Registry System: 1-Boc-4-(3-oxopropyl)piperidine(165528-85-8)

Safety Data

• Hazardous Substances Data: 165528-85-8(Hazardous Substances Data)

Usage

General Description

1-Boc-4-(3-oxopropyl)piperidine is a chemical compound with the molecular formula C15H27NO3. It is a white solid that is soluble in organic solvents and has a melting point of about 44-47 degrees Celsius. 1-Boc-4-(3-oxopropyl)piperidine is commonly used in organic synthesis as a building block for the construction of more complex molecules. It has potential applications in pharmaceutical research and development, particularly in the synthesis of drugs and biologically active compounds. 1-Boc-4-(3-oxopropyl)piperidine is an important intermediate in the preparation of various pharmaceutical agents and other organic compounds.

Upstream product

• 156185-63-6 N-Boc-piperidin-4-yl-propanol 
• 7037-49-2 3-(piperidin-4-yl)propan-1-ol 
• 2629-72-3 4-(3-Hydroxypropyl)pyridine 
• 79-37-8 oxalyl dichloride 
• 107-02-8 acrolein 

Downstream Products

• 165529-91-9 methyl (R,S)-8-<4--1(Z)-butenyl>-2,3,4,5-tetrahydro-3-oxo-4-(2-phenylethyl)-1H-1,4-benzodiazepine-2-acetate 
• 165529-90-8 methyl (R,S)-8-<4--1(E)-butenyl>-2,3,4,5-tetrahydro-3-oxo-4-(2-phenylethyl)-1H-1,4-benzodiazepine-2-acetate 
• 142355-83-7 4-(1-tert-butoxycarbonylpiperidin-4-yl)-butan-1-ol 
• 142355-81-5 tert-butyl 4-(4-bromobutyl)piperidine-1-carboxylate 
• 142356-28-3 4-{4-[4-((S)-2-Amino-2-carboxy-ethyl)-phenoxy]-butyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 142373-59-9 4-(4-{4-[(S)-2-(Butane-1-sulfonylamino)-2-carboxy-ethyl]-phenoxy}-butyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 142355-84-8 4-{4-[4-((S)-2-Benzyloxycarbonylamino-2-carboxy-ethyl)-phenoxy]-butyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 403857-10-3 3-(2-{(S)-2-(Butane-1-sulfonylamino)-3-[4-(4-piperidin-4-yl-butoxy)-phenyl]-propionyloxy}-4,6-dimethoxy-phenyl)-3-methyl-butyric acid 
• 403857-09-0 4-[4-(4-{2-(butane-1-sulfonylamino)-2-[2-(2-carboxy-1,1-dimethyl-ethyl)-3,5-dimethoxy-phenoxycarbonyl]-ethyl}-phenoxy)-butyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 403857-08-9 1-N-Boc-tirofiban-2-[3-[(1-t-butyl-1,1-dimethylsilyl)oxyl]-1,1-dimethylpropyl]-4,6-dimethoxyphenol 
• 223587-35-7 4-[4-(2-carboxymethyl-3-oxo-4-phenethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-8-yl)-but-3-enyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 223587-32-4 4-[4-(2-carboxymethyl-3-oxo-4-phenethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-8-yl)-but-3-enyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1350447-67-4 C₁₅H₂₀N₂O₄S 
• 1350447-69-6 C₁₇H₂₃NO₄S 

Relevant articles and documents

NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF

The present invention relates to a method for preparing a biomaterial having selectively functionalized tyrosine, a biomaterial having selectively functionalized tyrosine, and a pharmaceutical composition containing the same as an active ingredient. The method for preparing a biomaterial to which a compound represented by formula 2 is coupled, of the present invention, allows the compound represented by formula 2 to be selectively coupled, in a high yield in a biomaterial, to tyrosine, which is present on the surface of an aqueous solution such that the coupling thereof to amino acids other than tyrosine does not occur and, when only one tyrosine is present, heterogeneous mixtures are not present and the inherent activity of the biomaterial is maintained, and thus the compound can be effectively used as a pharmaceutical composition containing a biomaterial drug as an active ingredient. In addition, the method can selectively functionalize tyrosine, and thus can be effectively used for tyrosine functionalization in a biomaterial.

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

Catalyst-Free Deaminative Functionalizations of Primary Amines by Photoinduced Single-Electron Transfer

The use of pyridinium-activated primary amines as photoactive functional groups for deaminative generation of alkyl radicals under catalyst-free conditions is described. By taking advantage of the visible light absorptivity of electron donor–acceptor complexes between Katritzky pyridinium salts and either Hantzsch ester or Et3N, photoinduced single-electron transfer could be initiated in the absence of a photocatalyst. This general reactivity platform has been applied to deaminative alkylation (Giese), allylation, vinylation, alkynylation, thioetherification, and hydrodeamination reactions. The mild conditions are amenable to a diverse range of primary and secondary alkyl pyridiniums and demonstrate broad functional group tolerance.