166824-01-7

Basic information

• Product Name: Benzenemethanol, a-[(1E)-2-(4-methylphenyl)ethenyl]-
• CAS NO: 166824-01-7
• Molecular Formula: C16H16O
• Molecular Weight: 224.302
• Mol File: 166824-01-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-[(1E)-2-(4-methylphenyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-[(1E)-2-(4-methylphenyl)ethenyl]-(166824-01-7)
• EPA Substance Registry System: Benzenemethanol, a-[(1E)-2-(4-methylphenyl)ethenyl]-(166824-01-7)

Safety Data

• Hazardous Substances Data: 166824-01-7(Hazardous Substances Data)

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 100-52-7 benzaldehyde 
• 4224-87-7 4-methyl-chalcone 
• 122-00-9 para-methylacetophenone 
• 98-86-2 acetophenone 
• 88330-56-7 2-Methyl-5-phenyl-3-p-tolyl-isoxazolidine 
• 1669-54-1 (E)-1-(4-methylphenyl)-3-phenyl-2-propen-1-ol 
• 22252-14-8 (E)-3-(4-methylphenyl)-1-phenyl-2-propen-1-one 

Downstream Products

• 4224-87-7 4-methyl-chalcone 
• 134539-87-0 1-methyl-4-(3-phenyl-1-propen-1-yl)benzene 
• 134539-86-9 1-methyl-4-(3-phenyl-2-propen-1-yl)benzene 
• 4224-96-8 3-phenyl-1-p-tolylprop-2-en-1-one 
• 1352733-26-6 (E)-5-(4-methylstyryl)-1-phenyl-1H-tetrazole 
• 1352733-07-3 (E)-5-styryl-1-(p-tolyl)-1Htetrazole 
• 62056-37-5 1-methyl-4-[(1E)-3-phenylprop-1-en-1-yl]benzene 
• 1669-50-7 1-phenyl-3-(4-tolyl)propan-1-one 
• 134430-88-9 (2E)-N-(4-methylphenyl)-3-phenylprop-2-enamide 
• 365410-94-2 trans-N-phenyl-3-tolyl propeneamide 

Relevant articles and documents

Direct Reduction of Allylic Alcohols Using Isopropanol as Reductant

The lithium cation-catalyzed direct reduction of allylic alcohols to alkenes using isopropanol as a hydride donor was developed. The hydride transfer of the in situ-generated lithium isopropoxide to an allylic cation is the key process in this transformation. The reaction generates only water and acetone as byproducts, which highlights the synthetic utility of this method. (Figure presented.).

Copper-catalyzed oxidative transformation of secondary alcohols to 1,5-disubstituted tetrazoles

A mild and convenient oxidative transformation of secondary alcohols to 1,5-disubstituted tetrazoles is uncovered by employing trimethylsilyl azide (TMSN3) as a nitrogen source in the presence of a catalytic amount of copper(II) perchlorate hexahydrate [Cu(ClO4)2 .6 H2O] (5 mol%) and 2,3-dichloro-5,6-dicyano-para- benzoquinone (DDQ) (1.2 equiv.) as an oxidant. This reaction is performed under ambient conditions and proceeds through C-C bond cleavage.

Allylic activation across an Ir-Sn heterobimetallic catalyst: Nucleophilic substitution and disproportionation of allylic alcohol

A nucleophilic substitution of allylic alcohols with carbon (arene, heteroarene, allyltrimethylsilane, and 1,3-dicarbonyl compound), sulfur (thiol), oxygen (alcohol), and nitrogen (sulfonamide) nucleophiles has been demonstrated using an in house developed [Ir(COD)(SnCl3)l(μ-Cl)]2 heterobimetallic catalyst in 1,2-dichloroethane to afford the corresponding allylic products in moderate to excellent yields. In 4-hydroxycoumarin, allylation occurs at the 3-position. The diaryl-substituted allylic alcohols undergo disproportionation in presence of the heterobimetallic catalyst to provide the corresponding alkenes and chalcones. An electrophilic mechanism is proposed from Hammett correlation study.