166940-44-9

Basic information

• Product Name: Benzenemethanol, -alpha-,2,4-trimethyl-, (-alpha-R)- (9CI)
• Synonyms: Benzenemethanol, -alpha-,2,4-trimethyl-, (-alpha-R)- (9CI)
• CAS NO: 166940-44-9
• Molecular Formula: C10H14O
• Molecular Weight: 150.21756
• Product Categories: PHENYL
• Mol File: 166940-44-9.mol
• Article Data: 19

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenemethanol, -alpha-,2,4-trimethyl-, (-alpha-R)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, -alpha-,2,4-trimethyl-, (-alpha-R)- (9CI)(166940-44-9)
• EPA Substance Registry System: Benzenemethanol, -alpha-,2,4-trimethyl-, (-alpha-R)- (9CI)(166940-44-9)

Safety Data

• Hazardous Substances Data: 166940-44-9(Hazardous Substances Data)

Upstream product

• 102877-07-6 1-(2,4-dimethylphenyl)ethanamine 
• 89-74-7 2,4-dimethylacetophenone. 
• 2234-20-0 2,4-dimethylstyrene 
• 7446-70-0 aluminium trichloride 
• 107-06-2 1,2-dichloro-ethane 
• 75-36-5 acetyl chloride 
• 108-38-3 m-xylene 
• 64-17-5 ethanol 
• 64-19-7 acetic acid 
• 99500-87-5 1-(2,4-dimethylphenyl)ethanol 
• 108-05-4 vinyl acetate 
• 123-62-6 propionic acid anhydride 

Downstream Products

• 168749-62-0 1-(2,4-Dimethyl-phenyl)-ethanol 
• 14679-18-6 2-(o,p-Dimethylphenyl)-aethyl-n-butyl-sulfid 
• 1613639-26-1 C₁₃H₁₈O₂ 
• 166940-44-9 (R)-1-(2,4-dimethylphenyl)ethan-1-ol 
• 1019527-08-2 N-(1-(2,4-dimethylphenyl)ethyl)aniline 
• 20871-92-5 2-(bromoethyl)-5-methyltoluene 

Relevant articles and documents

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Manganese-Catalyzed Enantioselective Hydrogenation of Simple Ketones Using an Imidazole-Based Chiral PNN Tridentate Ligand

A series of Mn(I) catalysts containing imidazole-based chiral PNN tridentate ligands with controllable 'side arm' groups have been established, enabling the inexpensive base-promoted asymmetric hydrogenation of simple ketones with outstanding activities (up to 8200 TON) and good enantioselectivities (up to 88.5percent ee). This protocol features wide substrate scope and functional group tolerance, thereby providing easy access to a key intermediate of crizotinib.

Bimetallic Catalysis: Asymmetric Transfer Hydrogenation of Sterically Hindered Ketones Catalyzed by Ruthenium and Potassium

An efficient protocol for the asymmetric reduction of sterically hindered ketones under transfer-hydrogenation conditions was developed. The corresponding chiral alcohols were obtained in good to excellent yields with enantiomeric excess values up to 99 %. The role of the cation associated with the base present in the reduction reaction was investigated. In contrast to previous studies on this catalyst system, potassium ions rather than lithium ions significantly enhanced the reaction outcome.