1672-88-4 Usage
Description
Furazidine, also known as Furagin, is an imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [3-(5-nitro-2-furyl)prop-2-en-1-ylidene]amino group. It is a nitrofuran antibiotic with properties similar to nitrofurantoin and is characterized as a yellow solid.
Uses
Used in Pharmaceutical Industry:
Furazidine is used as an antibiotic for the treatment of urinary tract infections. It demonstrates similar efficacy to Ciprofloxacin in treating acute cystitis, although the duration of therapy is longer. The antibiotic properties of Furazidine make it a valuable compound in the pharmaceutical industry for combating bacterial infections.
Used in Antimicrobial Applications:
As a nitrofuran antibiotic, Furazidine is employed in various antimicrobial applications to combat bacterial infections, particularly those affecting the urinary tract. Its effectiveness in treating such infections highlights its importance in the field of medicine and healthcare.
Check Digit Verification of cas no
The CAS Registry Mumber 1672-88-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,7 and 2 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1672-88:
(6*1)+(5*6)+(4*7)+(3*2)+(2*8)+(1*8)=94
94 % 10 = 4
So 1672-88-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N4O5/c15-8-6-13(10(16)12-8)11-5-1-2-7-3-4-9(19-7)14(17)18/h1-5H,6H2,(H,12,15,16)/b2-1+,11-5+
1672-88-4Relevant articles and documents
Synthesis method of 1-((3-(5-nitro-2-furyl)allylidene)amino) hydantoin
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Paragraph 0043; 0045; 0046; 0047; 0050; 0052; 0054, (2018/11/22)
The invention discloses a synthesis method of 1-((3-(5-nitro-2-furyl)allylidene)amino) hydantoin. The synthesis method is characterized by including: taking 5-nitrofuranacrolein and propyl aminohydantoin as main raw materials, allowing one-step condensation reaction to prepare a target compound crude product, and refining and purifying N, N-dimethylformamide to obtain 1-((3-(5-nitro-2-furyl)allylidene)amino) hydantoin, wherein a chemical reaction formula is shown as follows. Compared with reported methods, the synthesis method has the advantages that reaction path is short, process is simple and convenient, the raw materials are easy to get, generation of a pollution byproduct-aldehyde during synthesis is avoided, and the method is high in yield, low in cost, few in three wastes and environment-friendly, and reaction conversion rate reaches 98%.
