167558-54-5

Basic information

• Product Name: Benzenamine, 2-(2,2-dibromoethenyl)-
• Synonyms: Benzenamine, 2-(2,2-dibromoethenyl)-
• CAS NO: 167558-54-5
• Molecular Formula: C8H7Br2N
• Molecular Weight: 276.958
• Mol File: 167558-54-5.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: Benzenamine, 2-(2,2-dibromoethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2-(2,2-dibromoethenyl)-(167558-54-5)
• EPA Substance Registry System: Benzenamine, 2-(2,2-dibromoethenyl)-(167558-54-5)

Safety Data

• Hazardous Substances Data: 167558-54-5(Hazardous Substances Data)

Upstream product

• 253684-24-1 1-(2,2-dibromovinyl)-2-nitrobenzene 
• 7468-67-9 o-formylbenzonitrile 
• 558-13-4 carbon tetrabromide 
• 552-89-6 2-nitro-benzaldehyde 
• 167558-53-4 1,1-Dibromo-2-(o-cyanophenyl)ethene 
• 5344-90-1 2-Aminobenzyl alcohol 
• 693794-60-4 2-(gem-dibromovinyl)-N-(tert-butoxycarbonyl)aniline 
• 167558-57-8 1,1-Dibromo-2-(o-carboxamidophenyl)ethene 

Downstream Products

• 863870-53-5 [2-(2,2-dibromovinyl)phenyl]-(4-fluorophenyl)amine 
• 537684-22-3 2-o-tolyl-1H-indole 
• 5784-95-2 2-(4-methoxyphenyl)-1H-indole 
• 863870-48-8 benzyl-[2-(2,2-dibromovinyl)-phenyl]-amine 
• 880153-78-6 tert-butyl (2-((2-(2,2-dibromovinyl)phenyl)amino)-2-oxoethyl)carbamate 
• 880154-00-7 2-methyl-3-oxo-2,3-dihydro-imidazo[1,2-a]indole-1-carboxylic acid benzyl ester 
• 1233516-74-9 2-(2,2-dibromovinyl)-1-isocyanatobenzene 
• 1259577-20-2 N-[2-(2,2-dibromoethenyl)phenyl]methanesulfonamide 
• 1259577-22-4 N-[2-(2,2-dibromoethenyl)phenyl]benzamide 
• 1072943-52-2 N-[2-(2,2-dibromovinyl)phenyl]-4-methylbenzenesulfonamide 
• 1290035-30-1 2-bromoethynylphenylamine 

Relevant articles and documents

Palladium-Catalyzed Domino Cyclization/Phosphorylation of gem-Dibromoolefins with P(O)H Compounds: Synthesis of Phosphorylated Heteroaromatics

We presented a palladium-catalyzed domino cyclization/phosphorylation of gem-dibromoolefins, which utilize H-phosphinates and secondary phosphine oxides as the phosphine sources, respectively. A variety of phosphorylated heteroaromatics were obtained in m

Synthesis of 3-Substituted Chalcogenophene-Fused Indoles from 2-Alkynylindoles

The intramolecular electrophilic cyclization of 3-organoselanyl-2-alkynylindoles providing the synthesis of 3-iodo-selenophene-fused indoles is reported herein. The strategy was extended to the preparation of 3-iodo-thiophene-fused indoles in a one-pot iodine-promoted thiolation of 2-alkynylindoles, followed by an electrophilic cyclization sequence. Besides, the synthesis of 3-butylselanyl-selenophene-fused indoles from 3-butylselanyl-2-alkynylindoles was also developed using iron(III) chloride and dibutyl diselenide to promote the cyclization and functionalization of the heterocycle. The identification of the alkyl halide intermediate afforded evidence to the proposed mechanism, which indicated that the reactions proceed through the formation of an iodonium ion, followed by a selenium 5-endo-dig cyclization, to afford the indole derivatives. The 3-iodo-selenonophene-fused indoles prepared were applied as substrates in copper-catalyzed cross-coupling reactions with thiols to give the Ullmann type products in good yields. (Figure presented.).

Pd-Catalyzed Tandem Coupling Reaction of 2-gem-Dibromovinylanilines and N-Tosylhydrazones to Construct 2-(1-phenylvinyl)-indoles

A novel palladium(0)-catalyzed intermolecular coupling reaction of 2-gem-dibromovinylanilines and N-tosylhydrazones was reported to construct 2-(1-phenylvinyl)-indoles efficiently. The indole bearing 1, 1-disubstituted alkenes were obtained in one step wi