16766-31-7

Basic information

• Product Name: 4,6-DICHLOROGUAIACOL
• Synonyms: 4,6-DICHLOROGUAIACOL
• CAS NO: 16766-31-7
• Molecular Formula: C₇H₆Cl₂O₂
• Molecular Weight: 193.02734
• Mol File: 16766-31-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 255.8°Cat760mmHg
• Flash Point: 108.5°C
• Appearance: /
• Density: 1.421g/cm³
• Vapor Pressure: 0.00994mmHg at 25°C
• Refractive Index: 1.57
• CAS DataBase Reference: 4,6-DICHLOROGUAIACOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-DICHLOROGUAIACOL(16766-31-7)
• EPA Substance Registry System: 4,6-DICHLOROGUAIACOL(16766-31-7)

Safety Data

• Hazardous Substances Data: 16766-31-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H6Cl2O2/c1-11-6-3-4(8)2-5(9)7(6)10/h2-3,10H,1H3

Upstream product

• 74672-01-8 3,5-dichloro-2-nitroanisole 
• 99847-06-0 (2,4-dichloro-6-methoxy-phenoxy)-acetic acid 
• 67-56-1 methanol 
• 63969-35-7 2,4-dichloro-6-diazocyclohexa-2,4-dien-1-one 
• 16766-30-6 4-Chloroguaiacol 
• 90-05-1 2-methoxy-phenol 
• 1120310-43-1 4-chloro-6,6-dimethoxycyclohexa-2,4-dienone 

Downstream Products

• 99847-06-0 (2,4-dichloro-6-methoxy-phenoxy)-acetic acid 
• 32520-91-5 [2-(2,4-Dichloro-6-methoxy-phenoxy)-ethyl]-dimethyl-amine 
• 32520-93-7 [2-(2,4-Dichloro-6-methoxy-phenoxy)-ethyl]-diethyl-amine 

Relevant articles and documents

Unanticipated participation of HCl in nucleophilic chlorination reaction: Expedient route to meta chlorophenols

o-Quinone monoketals participated in a 1,4-addition reaction with HCl furnishing m-chlorophenols in high yields. Several readily available o-quinone monoketals were selected to display the generality of this serendipitous and unprecedented reaction and the results are presented herein.

Crown Ethers from o-Quinone Diazides and Oxetane

The carbenes 11, generated by photolysis of the di- and tetrachloro-o-quinone diazides 10, react with oxetane in a 1:3 ratio to give the 15-membered crown ethers 19.In the presence of methanol, the oxonium ions 12 are trapped with formation of 1-(aryloxy)-3-methoxypropanes (13).In the absence of additional nucleophiles, 12 react with oxetane until the chain length is appropriate for inverting intramolecular attack of the aryl oxide at the α-carbon atom of the oxonium ion (18 -> 19). Key Words: Carbonyl carbenes/ Oxygen ylides/ Displacement, nucleophilic, intramolecular/ Carbenes/ Ylides