168167-03-1

Basic information

• Product Name: 3-[3-(4-Fluoro-benzyl)-5-(toluene-4-sulfonylamino)-indol-1-yl]-propionic acid methyl ester
• CAS NO: 168167-03-1
• Molecular Weight: 480.56
• Mol File: 168167-03-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[3-(4-Fluoro-benzyl)-5-(toluene-4-sulfonylamino)-indol-1-yl]-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[3-(4-Fluoro-benzyl)-5-(toluene-4-sulfonylamino)-indol-1-yl]-propionic acid methyl ester(168167-03-1)
• EPA Substance Registry System: 3-[3-(4-Fluoro-benzyl)-5-(toluene-4-sulfonylamino)-indol-1-yl]-propionic acid methyl ester(168167-03-1)

Safety Data

• Hazardous Substances Data: 168167-03-1(Hazardous Substances Data)

Upstream product

• 168166-54-9 methyl 3-(4-fluorophenylmethyl)-5-nitro-1H-indole-1-propanoate 
• 168166-37-8 3-(4-fluorophenylmethyl)-5-nitro-1H-indole 
• 63416-70-6 3-(4-fluorophenyl)propanal 
• 7116-38-3 ethyl 3-(4-fluorophenyl)propanoate 
• 98-59-9 p-toluenesulfonyl chloride 
• 168166-72-1 3-[5-Amino-3-(4-fluoro-benzyl)-indol-1-yl]-propionic acid methyl ester 

Relevant articles and documents

Thromboxane modulating agents. 2. Thromboxane receptor antagonists derived from the thromboxane synthase inhibitor dazmegrel

The design of dual thromboxane synthase inhibitor/thromboxane receptor antagonists (e.g. 15) based on the structure of the thromboxane synthase inhibitor dazmegrel is described. More potent receptor antagonists (e.g. 16c) result from replacement of the pyridinyl substituent with 4-fluorophenyl. Modelling suggests the existence of more than one site capable of interacting with the aryl sulfonamide of TxA2 receptor antagonists.