168640-83-3

Basic information

• Product Name: 3,4,5-Tris-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-benzoic acid methyl ester
• Synonyms: 3,4,5-Tris-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-benzoic acid methyl ester
• CAS NO: 168640-83-3
• Molecular Weight: 787.825
• Mol File: 168640-83-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,4,5-Tris-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4,5-Tris-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-benzoic acid methyl ester(168640-83-3)
• EPA Substance Registry System: 3,4,5-Tris-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-benzoic acid methyl ester(168640-83-3)

Safety Data

• Hazardous Substances Data: 168640-83-3(Hazardous Substances Data)

Upstream product

• 99-24-1 methyl galloate 
• 168640-82-2 11-azido-3,6,9-trioxa-undecanyl p-toluenesulfonate 
• 37860-51-8 tetraethylene glycol di(p-toluenesulfonate) 
• 112-60-7 Tetraethylene glycol 
• 149-91-7 3,4,5-trihydroxybenzoic acid 
• 35388-10-4 3,4,5-trihydroxybenzoyl chloride 

Downstream Products

• 168640-86-6 3,4,5-Tris-[2-(2-{2-[2-(2-chloro-acetylamino)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-benzoic acid methyl ester 
• 168640-84-4 3,4,5-Tris-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-benzoic acid 
• 168640-85-5 3,4,5-Tris-(2-{2-[2-(2-amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-benzoic acid methyl ester 

Relevant articles and documents

Synthesis of hyperbranched glycodendrimers incorporating α-thiosialosides based on a gallic acid core

Hyperbranched glycodendrimers containing sialic acid residues were synthesized in order to further understand the multivalency effect and its role in carbohydrate-protein interactions. Gallic acid 7 as trivalent core and oligoethylene glycol derivatives as hydrophilic spacers were used to scaffold the dendritic backbones. α-Thiosialoside 16 was conjugated onto N-chloroacetylated dendritic precursors 13, 14, and 26 by nucleophilic substitution to afford trivalent 17, 18, and nonavalent 27 sialodendrimers. Complete sugar deprotection furnished water-soluble α-thiosialodendrimers 21, 22, and 29, which were used in protein-binding studies. Turbidimetric analysis confirmed the strong potential of sialodendrimers 29 having nine readily accessible sialic acid residues to bind, cross-link, and precipitate two different lectins. Preliminary results indicated that nonavalent α-sialodendrimer 29 had a greater affinity towards dimeric wheat germ agglutinin (WGA) and the lectin from the slug Limax flavus (LFA) than the corresponding trivalent glycodendrimers 21 and 22.