169181-43-5

Basic information

• Product Name: 1-chloro-2-<(2-hydroxy-4-nitrophenyl)amino>ethenyl-p-tolyl sulfone
• Synonyms: 1-chloro-2-<(2-hydroxy-4-nitrophenyl)amino>ethenyl-p-tolyl sulfone
• CAS NO: 169181-43-5
• Molecular Weight: 368.798
• Mol File: 169181-43-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-chloro-2-<(2-hydroxy-4-nitrophenyl)amino>ethenyl-p-tolyl sulfone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-2-<(2-hydroxy-4-nitrophenyl)amino>ethenyl-p-tolyl sulfone(169181-43-5)
• EPA Substance Registry System: 1-chloro-2-<(2-hydroxy-4-nitrophenyl)amino>ethenyl-p-tolyl sulfone(169181-43-5)

Safety Data

• Hazardous Substances Data: 169181-43-5(Hazardous Substances Data)

Upstream product

• 17200-30-5 6-nitrobenzo[d]oxazole 
• 7569-26-8 chloromethyl p-tolylsulfone 

Relevant articles and documents

The vicarious nucleophilic substitution of hydrogen and related reactions in nitrobenzoxazoles

5- and 6-nitrobenzoxazoles 3 and 4 react with nucleophiles exclusively at C-2, giving ring opening products. If position 2- is blocked with phenyl substituent the reaction takes place in the carbocyclic ring affording the VNS products. 2-Methylthio-5-nitrobenzoxazole 7 and its 6-nitro isomer 8 give products which result from addition of a nucleophile to the carbocyclic ring (VNS) as well as to the heterocyclic ring (S(N)Ar and ring cleavage). 2-Methylthiobenzoxazoles can be readily converted to the corresponding benzoxazolones via oxidative hydrolysis.