169615-68-3

Basic information

• Product Name: 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-one
• Synonyms: 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-one
• CAS NO: 169615-68-3
• Molecular Weight: 224.259
• Mol File: 169615-68-3.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-one(169615-68-3)
• EPA Substance Registry System: 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-one(169615-68-3)

Safety Data

• Hazardous Substances Data: 169615-68-3(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 514826-79-0 3-hydroxy-2-iodophenol trifluoromethanesulfonate 
• 514826-78-9 2-iodo-1,3-phenylene bis(trifluoromethanesulfonate) 
• 108-46-3 recorcinol 
• 41046-67-7 2-iodoresorcinol 
• 108-95-2 phenol 
• 31575-75-4 2-bromophenyl benzyl ether 
• 2678-54-8 ketene diethyl acetal 
• 95-56-7 2-hydroxybromobenzene 
• 100-44-7 benzyl chloride 
• 591-20-8 3-Bromophenol 
• 1612240-17-1 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-ol 
• 53087-13-1 3-(benzyloxy)phenyl bromide 
• 24318-02-3 1-(benzyloxy)-3-chlorobenzene 

Downstream Products

• 1612240-17-1 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-ol 
• 20289-27-4 7-benzyloxyindole 

Relevant articles and documents

SULFONIMIDAMIDE COMPOUNDS AS NLRP3 MODULATORS

Described herein are compounds of Formula (I), Formula (I-A), and Formula (I-B), solvates thereof, tautomers thereof, and pharmaceutically acceptable salts of the foregoing, Further described herein are methods of inhibiting NLRP3 using said compounds, and methods of and compositions useful in treating NLRP3-dependent disorders.

Skeleton Reorganization of Substituted Benzocyclobutenols through Rh-Catalyzed C-C Bond Cleavage Manipulated by Hydrogen Transfer

Although transition-metal-catalyzed C-C bond activation has been investigated extensively, C-C bond cleavage manipulated by hydrogen transfer has been unexplored. In this work, we disclose a skeleton reorganization of alkene-tethered benzocyclobutenols through Rh-catalyzed C-C bond cleavage coupled with intra- and intermolecular hydrogen transfer. The reaction pathway was well-tuned by the catalytic systems. As a result, divergent benzofurans bearing 4-β-hydroxy or 4-β-keto moieties were synthesized under pH- and redox-neutral conditions.

MODULATORS OF THR-β AND METHODS OF USE THEREOF

Disclosed herein are compounds of Formula (I) or a pharmaceutically acceptable salt, prodrug, amide or ester thereof, where i) TL is a moiety of Formula IlIa, lIIb, IlIa, IIIb, IIIc, or IIId; ii) CE is a moiety of Formula IV; iii) HD is a moiety of Formula V or VI; where the substituents are as defined herein. Disclosed are also pharmaceutical compositions comprising the above compounds, and methods of treating disease by administering or contact a patient with one or more of the above compounds.