170158-29-9Relevant articles and documents
Studies on reactions of nucleoside H-phosphonates with bifunctional reagents. Part 3. Further studies on transesterification of nucleoside H- phosphonate diesters with amino alcohols
Sobkowski,Stawinski,Sobkowska,Kraszewski
, p. 839 - 842 (1995)
Reactions of 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl 2-cyanoethyl phosphonate with alcohols, amines and amino alcohols in pyridine are described. Transesterification was found to be faster than β-elimination of 2-cyanoethyl group.