102987-83-7

Basic information

• Product Name: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(2-cyanoethyl phosphonate)
• CAS NO: 102987-83-7
• Molecular Formula: C34H36N3O9P
• Molecular Weight: 661.648
• Mol File: 102987-83-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(2-cyanoethyl phosphonate)(CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(2-cyanoethyl phosphonate)(102987-83-7)
• EPA Substance Registry System: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(2-cyanoethyl phosphonate)(102987-83-7)

Safety Data

• Hazardous Substances Data: 102987-83-7(Hazardous Substances Data)

Upstream product

• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 98796-51-1 5'-O-(4,4'-dimethoxytrityl)-2'-deoxythymidine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite] 
• 78635-98-0 3'-O-levulinoylthymidine 
• 863507-20-4 5'-OH-dG^i-Bupo_CNEdG^i-Bu-3'-O-Lev 

Downstream Products

• 105784-94-9 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl ethyl phosphonate 
• 130288-81-2 5'-O-dimethoxytrityl-2'-deoxythymidine-3'-H-phosphonate 
• 170158-29-9 2-aminoethyl 2-cyanoethyl phosphonate 
• 118149-31-8 C₄₃H₄₇N₄O₁₄PS 

Relevant articles and documents

Solid phase oligonucleotide synthesis by using β-CE H-phosphonate approach

A new approach to the solid phase synthesis of oligonucleotide is described, which is based on oxidative coupling of nucleoside 3′-β-CE H-phosphonates in presence of N-Bromosuccinimide (NBS) as a coupling agent.

High-yield solution-phase synthesis of di- and trinucleotide blocks assisted by polymer-supported reagents

(Chemical Equation Presented) A new solution-phase phosphoramidite approach is reported for oligonucleotide synthesis employing recyclable solid-supported reagents. It uses polyvinyl pyridinium tosylate as the activator of a nucleoside-3′-O-phosphoramidit

Commercially available 5'-DMT phosphoramidites as reagents for the synthesis of vinylphosphonate-linked oligonucleic acids.

[reaction: see text]. Commercially available cyanoethyl phosphoramidites derived from T, d(C), d(A), and d(G) were hydrolyzed (1H-tetrazole, MeCN/H2O) to give the corresponding H-phosphonates in excellent yields. Palladium(0)-catalyzed cross-coupling of e