105784-94-9

Basic information

• Product Name: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(ethyl phosphonate)
• CAS NO: 105784-94-9
• Molecular Formula: C33H37N2O9P
• Molecular Weight: 636.639
• Mol File: 105784-94-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(ethyl phosphonate)(CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(ethyl phosphonate)(105784-94-9)
• EPA Substance Registry System: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(ethyl phosphonate)(105784-94-9)

Safety Data

• Hazardous Substances Data: 105784-94-9(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 102987-83-7 5′-O-(4,4′-dimethoxytrityl)thymidine-3′-O-[2-cyanoethyl]phosphonate 
• 1000692-08-9 C₃₃H₃₇N₂SPO₈ 
• 50571-26-1 5'-O-dimethoxytritylthymidine 3'-H-phosphonate 
• 157793-52-7 p-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl phosphonate 

Downstream Products

• 762-04-9 phosphonic acid diethyl ester 
• 157793-53-8 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl N-butylphosphonamidate 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 170158-36-8 bis(6-aminohexyl) phosphonate 

Relevant articles and documents

Nucleoside H-phosphonates, XXII: Synthesis and properties of new nucleotide analogues - H-phosphonothiolate diesters

Condensation of nucleoside 3′-H-phosphonate monoesters with various thiols, promoted by condensing agents, provides a convenient access to a new class of H-phosphonate analogues, H-phosphonothiolate diesters. Chemical properties, relevant to possible appl

Studies on Reactions of Nucleoside H-Phosphonates with Bifunctional Reagents. Part 2. Stability of Nucleoside H-Phosphonate Diesters in the Presence of Amino Alcohols

H-Phosphonate diesters undergo transesterification with amino alcohols to afford as primary products the mixed and symmetrical H-phosphonate esters.Alcohols react similarly but only in the presence of an external base or in basic solvent.The rate and the course of transesterification strongly depend on the reaction conditions, the reactivity of the H-phosphonate diester used, and the nature of the amino alcohol.