17019-26-0

Basic information

• Product Name: 1,2-Propanedione, 1-phenyl-, 2-oxime, (E)-
• CAS NO: 17019-26-0
• Molecular Formula: C9H9NO2
• Molecular Weight: 163.176
• Mol File: 17019-26-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1,2-Propanedione, 1-phenyl-, 2-oxime, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Propanedione, 1-phenyl-, 2-oxime, (E)-(17019-26-0)
• EPA Substance Registry System: 1,2-Propanedione, 1-phenyl-, 2-oxime, (E)-(17019-26-0)

Safety Data

• Hazardous Substances Data: 17019-26-0(Hazardous Substances Data)

Usage

General Description

1,2-Propanedione, 1-phenyl-, 2-oxime, (E)- is a chemical compound also known as 2-Phenyl-2-propanone oxime, which is a colorless to light yellow liquid at room temperature. It is used as a chemical intermediate in the production of various pharmaceuticals, agrochemicals, and fragrances. It is also commonly used as a reagent in organic synthesis and as a chelating agent in coordination chemistry. 1,2-Propanedione, 1-phenyl-, 2-oxime, (E)- has potential applications in the fields of medicine, agriculture, and fragrance manufacturing, and its versatile properties make it a valuable addition to various chemical processes.

Upstream product

• 93-55-0 1-phenyl-propan-1-one 
• 110-46-3 isopentyl nitrite 
• 17019-18-0 anti-methylphenylglyoxime 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 7664-93-9 sulfuric acid 
• 14897-67-7 2-nitropropiophenone 
• 29024-92-8 1-hydroximino-1-phenylacetone 
• 25388-20-9 3-methyl-4-phenylisoxazole 
• 28867-78-9 (Z)-1-phenyl-1,2-propanedione 2-oxime 

Downstream Products

• 14838-15-4 u-2-amino-1-phenylpropan-1-ol 
• 60-15-1 2-amino-1-phenylpropane 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 5265-18-9 (+/-)-cathinone 
• 124616-07-5 1-[(Z)-Isopropylimino]-1-phenyl-propan-2-one oxime 
• 61487-86-3 C₁₉H₁₈N₂O₅ 
• 190434-51-6 (E)-2-(methoxyimino)-1-phenylpropan-1-one 
• 1062193-43-4 (R,R)-1,1'-(cyclohexane-1,2-diyl)bis(4-methyl-5-phenylimidazole)-3,3'-dioxide 
• 1062193-47-8 (S,S)-1,1'-(cyclohexane-1,2-diyl)bis(4-methyl-5-phenylimidazole)-3,3'-dioxide 
• 2549-30-6 4-Methyl-2,5-diphenyloxazole N-oxide 
• 71087-82-6 (E)-2-(acetoxyimino)-1-phenylpropan-1-one 

Relevant articles and documents

Visible-Light-Induced Transition-Metal-Free Nitrogen-Centered Radical Strategy for the Synthesis of 2-Acylated 9 H-Pyrrolo[1,2- a]indoles

A convenient and efficient visible-light-induced tandem acylation/cyclization of N-propargylindoles with aryl- or alkyl-substituted acyl oxime esters for the synthesis of 2-acyl-substituted 9H-pyrrolo[1,2-a]indoles under transition-metal-free conditions, which proceeds via nitrogen-centered radical-mediated cleavage of the C-C σ-bond in acyl oxime esters, is established. The aryl or alkyl acyl radicals, which come from acyl oxime esters, attack the C-C triple bonds in N-propargylindoles and then go through intramolecular cyclization/isomerization.

Discovery of a series of ruthenium(II) derivatives with α-dicarbonylmonoxime as novel inhibitors of cancer cells invasion and metastasis

A series of novel ruthenium(II)-cymene complexes (1–9) with substituted α-dicarbonylmonoximes of general formula [Ru(η6-cymene)(L)Cl] (L?=?N,O-chelating bidentate α-dicarbonylmonoxime derivatives) have been synthesized and characterized by elemental analysis, IR, 1H NMR, 13C NMR spectroscopies, and in three cases by single crystal X-ray diffraction analysis. The most effective compound 9 displays remarkable anti-invasion and anti-metastasis properties without apparent cytotoxicity toward three different human cancer cell lines (MCF-7, Hela and HepG2). Further protein level studies suggest that the anti-metastasis activity of the complexes may result from the increasing expression of E-cadherin and reducing expression of Vimentin.

Beckmann rearrangement of α-oximinoketones

The Beckmann rearrangement of α-oximinoketones gives benzoic acids as chief isolable products. Both first order and second order Beckmann rearrangements have been observed. The occurrence of first order Beckmann rearrangement in these oximinocarbonyl compounds is confirmed through the identification of the products obtained.