170367-69-8

Basic information

• Product Name: (R)-3-BOC-AMINO-BUTYLAMINE
• Synonyms: (R)-3-BOC-AMINO-BUTYLAMINE;Carbamic acid, [(1R)-3-amino-1-methylpropyl]-, 1,1-dimethylethyl ester (9CI);(R)-3-N-Boc-butane-1,3-diamine;Carbamic acid, N-[(1R)-3-amino-1-methylpropyl]-, 1,1-dimethylethyl ester;3(R)-Boc-aMino-butylaMine;(R)-tert-butyl 4-aMinobutan-2-ylcarbaMate;(R)-3-(Boc-amino)butanamine
• CAS NO: 170367-69-8
• Molecular Formula: C₉H₂₀N₂O₂
• Molecular Weight: 188.27
• Product Categories: N-BOC
• Mol File: 170367-69-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 282.6±23.0 °C(Predicted)
• Appearance: /
• Density: 0.972±0.06 g/cm3(Predicted)
• Refractive Index: 1.456
• Storage Temp.: 2-8°C(protect from light)
• PKA: 12.44±0.46(Predicted)
• CAS DataBase Reference: (R)-3-BOC-AMINO-BUTYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-BOC-AMINO-BUTYLAMINE(170367-69-8)
• EPA Substance Registry System: (R)-3-BOC-AMINO-BUTYLAMINE(170367-69-8)

Safety Data

• Hazardous Substances Data: 170367-69-8(Hazardous Substances Data)

Usage

General Description

(R)-3-BOC-AMINO-BUTYLAMINE is a chemical compound with the molecular formula C9H20N2O2 and a molecular weight of 188.27 g/mol. It is a derivative of butylamine and contains a BOC (tert-butoxycarbonyl) protecting group on the amino group. The compound is commonly used in organic synthesis and medicinal chemistry as a building block for the synthesis of various compounds. It has applications in the production of pharmaceuticals, agrochemicals, and other fine chemicals. (R)-3-BOC-AMINO-BUTYLAMINE is a versatile and useful compound in the field of chemical and pharmaceutical research.

InChI:InChI=1/C9H20N2O2/c1-7(5-6-10)11-8(12)13-9(2,3)4/h7H,5-6,10H2,1-4H3,(H,11,12)/t7-/m1/s1

Upstream product

• 170367-68-7 (2-cyano-1(R)-methylethyl)carbamic acid, 1,1-dimethylethyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 126301-16-4 (2R)-2-[(tert-butoxycarbonyl)amino]propyl methanesulfonate 
• 79069-13-9 (R)-2-tertbutoxycarbonylamino-1-propanol 

Downstream Products

• 875680-89-0 (R)-N¹-(o-nitrophenylsulfonyl)-N³-(tert-butyloxycarbonyl)-1,3-diaminobutane 
• 875680-91-4 (R)-N¹-phthaloyl-N⁵-(o-nitrophenylsulfonyl)-N⁸-(tert-butyloxycarbonyl)-1,8-diamino-5-azanonane 
• 932032-30-9 (R)-N⁵-(o-nitrophenylsulfonyl)-N⁸-(tert-butyloxycarbonyl)-8-amino-5-aza-1-iodononane 
• 932032-31-0 (R)-N¹²-(tert-butyloxycarbonyl)-N⁹-(o-nitrophenylsulfonyl)-1,12-diamino-4,9-diazatridecane 
• 170367-70-1 [1(R)-methyl-3-[(phenylmethyl)amino]propyl]carbamic acid, 1,1-dimethylethyl ester 
• 170367-71-2 3-[(3-cyanopropyl)(phenylmethyl)amino-1(R)-methylpropyl]carbamic acid, 1,1-dimethylethyl ester 
• 170367-72-3 3-[(4-aminobutyl)(phenylmethyl)amino-1(R)-methylpropyl]carbamic acid, 1,1-dimethylethyl ester 
• 252353-69-8 [3-[[4-(2,4-dioxo-3-oxazolidinyl)butyl](phynylmethyl)amino]-1-methylpropyl]carbamic acid, 1,1-dimethylethyl ester (R) 
• 170367-76-7 2,2,6-trimethyl-4,15-dioxo-9-(phenylmethyl)-3,16-dioxa-5,9,14-triazaoxadecan-18-oic acid (R) 
• 170367-82-5 [21-[[(1,1-dimethylethoxy)carbonyl]amino]-1,25,25-trimethyl-10,12,23-trioxo-4-(phenylmethyl)-24-oxa-4,9,13,20,22-pentaaza-21-hexacosen-1-yl]carbamic acid, 1,1-dimethylethyl ester (R) 
• 170367-78-9 [4-[[3-[[(1,1-dimethylethoxy)carbonyl]amino]butyl](phenylmethyl)amino]butyl]carbamic acid, 11-[[(1,1-dimethylethoxy)carbonyl]amino]-15,15-dimethyl-2,13-dioxo-14-oxa-3,4,12-triaza-11-hexadecen-1-yl ester (R) 

Relevant articles and documents

TRIAZACYCLODODECANSULFONAMIDE ("TCD")-BASED PROTEIN SECRETION INHIBITORS

Provided herein are triazacyclododecansulfonamide ("TCD")-based protein secretion inhibitors, such as inhibitors of Sec61, methods for their preparation, related pharmaceutical compositions, and methods for using the same. For example, provided herein are compounds of Formula (I) and pharmaceutically acceptable salts and compositions including the same. The compounds disclosed herein may be used, for example, in the treatment of diseases including inflammation and/or cancer.

POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY

The present invention is to provide a novel compound (I), having the anti-virus activity, particularly the HIV integrase inhibitory activity, and a drug containing the same, particularly an anti-HIV drug, as well as a process and an intermediate thereof. Compound (I) wherein Z1 is NR4; R1 is hydrogen or lower alkyl; X is a single bond, a hetero atom group selected from O, S, SO, SO2 and NH, or lower alkylene or lower alkenylene in which the hetero atom group may intervene; R2 is optionally substituted aryl; R3 is hydrogen, a halogen, hydroxy, optionally substituted lower alkyl etc; and R4 and Z2 part taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.

Synthesis of (R)- and (S)-isomers of 1-methylspermidine

Previously unknown (R)- and (S)-isomers of 1,8-diamino-5-azanonane were prepared starting from (R)- and (S)-2-aminopropanols.