170642-23-6Relevant articles and documents
Antimalarial activity of a new family of analogues of manzamine A
Winkler, Jeffrey D.,Londregan, Allyn T.,Hamann, Mark T.
, p. 2591 - 2594 (2007/10/03)
Manzamine A represents an important lead structure for the development of novel antimalarial chemotherapies. The synthesis and biological evaluation of a group of simplified analogues of manzamine A, which were designed to examine the roles of the A and D
The imine (+)-pseudoephedrine glycinamide: A useful reagent for the asymmetric synthesis of (R)-α-amino acids
Guillena, Gabriela,Najera, Carmen
, p. 181 - 183 (2007/10/03)
The new imine derived from Myers (+)-pseudoephedrine glycinamide can be diastereoselectively alkylated with alkyl halides at room temperature using NaOEt or LiO-tert-Bu as bases under phase transfer conditions. Hydrolysis to the corresponding alkylated products was easily achieved under mild conditions to afford (R)-α-amino acids.
A practical method for the synthesis of D- or L-α-amino acids by the alkylation of (+)- or (-)-pseudoephedrine glycinamide
Myers, Andrew G.,Gleason, James L.,Yoon, Taeyoung
, p. 8488 - 8489 (2007/10/02)
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