171019-30-0Relevant articles and documents
Asymmetric nitrone-vinyl sulfoxide cycloadditions
Louis, Chantal,Hootele, Claude
, p. 109 - 131 (2007/10/03)
The cycloaddition of (Z) and (E)-vinyl sulfoxides with cyclic nitrones 1 and 2 is reported. Best diastereoselection is achieved with (Z)-vinyl sulfoxides 7a-d as dipolarophiles. This methodology allows the highly stereoselective synthesis of (+)-sedridine 9a, (-)-hygroline 10 and (-)-(2S)-N-carbomethoxypelletierine 11a.