171258-00-7Relevant articles and documents
Intermolecular Three-Component Synthesis of Fluorene Derivatives by a Rhodium-Catalyzed Stitching Reaction/Remote Nucleophilic Substitution Sequence
Nishida, Masaki,Lee, Donghyeon,Shintani, Ryo
, p. 8489 - 8500 (2020/07/17)
A three-component synthesis of multisubstituted fluorene derivatives has been developed by devising a rhodium-catalyzed stitching reaction/remote nucleophilic substitution sequence. A variety of nucleophiles can be installed in the second step including both heteroatom and carbon nucleophiles. An efficient synthesis of 5H-benzo[a]fluoren-5-ones has also been realized using N-(2-alkynyl)benzoylpyrrole as the reaction partner through a new reaction pathway.
General Preparation of 3-Alkyl-1-Naphthols
Makra, Ferenc,Rohloff, John C.,Muehldorf, A. V.,Link, John O.
, p. 6815 - 6818 (2007/10/02)
Potassium enolates derived from readily available o-alkynylacetophenones undergo intramolecular cycloaromatization on heating to afford 3-alkyl-1-naphthols in good yields. - Key words: Cycloaromatization, enynone, ynenone, 3-alkyl-1-naphthol.