17193-36-1

Basic information

• Product Name: erythro-N-(tert-butoxycarbonyl)-β-hydroxy-L-phenylalanine methyl ester
• CAS NO: 17193-36-1
• Molecular Weight: 295.335
• Mol File: 17193-36-1.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: erythro-N-(tert-butoxycarbonyl)-β-hydroxy-L-phenylalanine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: erythro-N-(tert-butoxycarbonyl)-β-hydroxy-L-phenylalanine methyl ester(17193-36-1)
• EPA Substance Registry System: erythro-N-(tert-butoxycarbonyl)-β-hydroxy-L-phenylalanine methyl ester(17193-36-1)

Safety Data

• Hazardous Substances Data: 17193-36-1(Hazardous Substances Data)

Upstream product

• 1070-19-5 N-(tert-butyloxycarbonyl) azide 
• 17193-41-8 methyl (2RS,3SR)-2-amino-3-hydroxy-3-phenylpropanoate hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 38114-29-3 (+/-)-methyl (βR)-β-hydroxy-1-phenylalaninate 
• 17193-41-8 (2RS,3RS)-2-amino-3-hydroxy-3-phenyl-propionic acid methyl ester; hydrochloride 
• 103-26-4 Methyl cinnamate 
• 81691-59-0 (2RS,3RS)-2,3-dihydroxy-3-phenyl-propionic acid methyl ester 
• 38114-29-3 (+/-)-methyl (βS)-β-hydroxy-1-phenylalaninate 
• 116129-92-1 methyl (2S,3S)-2-amino-3-hydroxy-3-phenylpropanoate 
• 32946-42-2 (2S,3S)-2-amino-3-hydroxy-3-phenylpropanoic acid 
• 1392010-99-9 ethyl-2-((tert-butoxycarbonyl)amino)-3-oxo-3-(thiophen-2-yl)propanoate 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 136642-82-5 methyl (4S,5R)-3-N-tert-butoxycarbonyl-5-phenyl-1,3-oxazolidin-2-oxo-4-carboxylate 
• 154409-62-8 methyl (S)-2-[bis(tert-butoxycarbonyl) amino]-3-phenylpropanoate 

Downstream Products

• 17193-37-2 N-t-Butoxycarbonyl-threo-DL-β-phenyl-Ser-amid 
• 136642-83-6 methyl (2S,3S)-2-((tert-butyloxycarbonyl)amino)-3-((methanesulfonyl)oxy)-3-phenylpropionate 
• 599201-28-2 Boc-β-OHPhe-OH 
• 38114-29-3 (+/-)-methyl (βR)-β-hydroxy-1-phenylalaninate 
• 38114-29-3 (+/-)-methyl (βS)-β-hydroxy-1-phenylalaninate 
• 158009-43-9 H-β-OH-Phe-OMe 
• 141394-65-2 (4S,5R)-2-Oxo-5-phenyl-oxazolidine-4-carboxylic acid methyl ester 
• 136620-85-4 (2R,3R)-2-((tert-butyloxycarbonyl)amino)-3-((4-methylbenzyl)thio)-3-phenylpropionic acid 
• 136620-83-2 methyl (2R,3R)-3-(acetylthio)-2-((tert-butyloxycarbonyl)amino)-3-phenylpropionate 
• 136620-84-3 methyl (2R,3R)-2-((tert-butyloxycarbonyl)amino)-3-((4-methylbenzyl)thio)-3-phenylpropionic acid 
• 17193-35-0 (2RS,3SR)-2-amino-3-hydroxy-3-phenyl-propionic acid amide 
• 17193-35-0 (2RS,3RS)-2-amino-3-hydroxy-3-phenyl-propionic acid amide 
• 63658-18-4 methyl (Z)-N-Boc-α,β-didehydrophenylalaninate 
• 116129-92-1 methyl (2S,3S)-2-amino-3-hydroxy-3-phenylpropanoate 

Relevant articles and documents

Methyl 2-[(tert-Butoxycarbonyl)amino]-3-hydroxy-3-phenylpropanoate: Synthesis of Erythro (±) Isomer by Reduction and Threo (±) Isomer by Inversion Method

Abstract: We report an efficient protocol for synthesis of methyl 2-[(tert-butoxycarbonyl) amino]-3-hydroxy-3-phenylpropanoate (Erythro (±)) by simple reduction and methyl 2-[(tert-butoxycarbonyl) amino]-3-hydroxy-3-phenylpropanoate (Threo (±)) by inversi

Asymmetric synthesis of 2,4,5-trisubstituted Δ2- thiazolines

Δ2-Thiazolines are interesting heterocycles that display a wide variety of biological characteristics. They are also common in chiral ligands used for asymmetric syntheses and as synthetic intermediates. Herein, we present asymmetric routes to

Asymmetric transfer hydrogenation coupled with dynamic kinetic resolution in water: Synthesis of anti -β-hydroxy-α-amino acid derivatives

The use of asymmetric transfer hydrogenation combined with dynamic kinetic resolution for the synthesis of β-hydroxy-α-(tert-butoxycarbonyl) amino esters in water is described. This procedure provides the desired amino alcohols in good yields, diastereoselectivities, and enantioselectivities. A surfactant is employed to achieve good yields due to the hydrophobic nature of both the catalyst and substrate. The reaction setup is operationally simple, and nondegassed water can be used as the solvent.