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172932-06-8

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172932-06-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 172932-06-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,2,9,3 and 2 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 172932-06:
(8*1)+(7*7)+(6*2)+(5*9)+(4*3)+(3*2)+(2*0)+(1*6)=138
138 % 10 = 8
So 172932-06-8 is a valid CAS Registry Number.

172932-06-8Downstream Products

172932-06-8Relevant articles and documents

Importance of the proximity and orientation of ligand-linkage to the design of cinnamate-GW9662 hybrid compounds as covalent PPAR agonists

Utsugi, Yuki,Kobuchi, Hirona,Kawamura, Yukio,Atito, Ahmed Salahelden Aboelhamd,Nagao, Masaya,Isoda, Hiroko,Miyamae, Yusaku

, (2019/06/05)

Covalent agonists of PPAR cause unique receptor conformational changes and behave as selective PPAR modulators, whereas there are few covalent agonists other than endogenous unsaturated fatty acids metabolites. Previously, we established a cell-based stra

Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid

Pfefferkorn, Jeffrey A.,Greene, Meredith L.,Nugent, Richard A.,Gross, Rebecca J.,Mitchell, Mark A.,Finzel, Barry C.,Harris, Melissa S.,Wells, Peter A.,Shelly, John A.,Anstadt, Robert A.,Kilkuskie, Robert E.,Kopta, Laurice A.,Schwende, Francis J.

, p. 2481 - 2486 (2007/10/03)

A novel series of nonnucleoside HCV NS5B polymerase inhibitors were prepared from (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid, a high throughput screening lead. SAR studies combined with structure based drug design focusing on the southern heterobiaryl region of the template led to the synthesis of several potent and orally bioavailable lead compounds. X-ray crystallography studies were also performed to understand the interaction of these inhibitors with HCV NS5B polymerase.

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