173031-63-5

Basic information

• Product Name: 2-Phenyl-2-(2,4,6-triisopropylbenzoyloxy)-1-propanol
• Synonyms: 2-Phenyl-2-(2,4,6-triisopropylbenzoyloxy)-1-propanol
• CAS NO: 173031-63-5
• Molecular Weight: 382.543
• Mol File: 173031-63-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Phenyl-2-(2,4,6-triisopropylbenzoyloxy)-1-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Phenyl-2-(2,4,6-triisopropylbenzoyloxy)-1-propanol(173031-63-5)
• EPA Substance Registry System: 2-Phenyl-2-(2,4,6-triisopropylbenzoyloxy)-1-propanol(173031-63-5)

Safety Data

• Hazardous Substances Data: 173031-63-5(Hazardous Substances Data)

Upstream product

• 98-85-1 1-Phenylethanol 
• 77256-62-3 1'-methylbenzyl 2,4,6-triisopropylbenzoate 
• 49623-71-4 2,4,6-triisopropylbenzoic acid 
• 173031-59-9 Methyl 2-phenyl-2-(2,4,6-triisopropylbenzyloxy)propionate 

Relevant articles and documents

Chiral Carbanions, 1. - Configurational Stability and Reactions of α-Acyloxy-Substituted α-Methylbenzyllithium Compounds

Racemic and optically active 1-phenylethyl esters of pivalic, (-)-camphanic and 2,4,6-triisopropylbenzoic acid were prepared.The esters 7a of pivalic acid were deprotonated with lithium 2,2,6,6-tetramethylpiperidide (Li-TMP) to form α-oxy-α-methylbenzyllithium compounds which are partly configurationally stable prior to acylation with starting material.Camphanic ester (-)-7b cannot be deprotonated by Li-TMP and t-BuLi is added to the ester function to afford ketone (-)-12a. 1-Phenylethyl 2,4,6-triisopropylbenzoates 16 were transformed within minutes to carbanions 19 by using s-BuLi/TMEDA in THF, hexane, toluene and s-BuLi without TMEDA in toluene/20percent diethyl ether at -78 deg C.The carbanions are configurationally stable only in toluene/20percent diethyl ether and racemise partly in the other solvents.They react with a variety of electrophiles with either retention or inversion (Me3SnCl) of configuration.Carbanions 19 rearrange on warming to -20 deg C to hydroxy ketone 24 with racemisation. - Keywords: Esters, 1-phenylethyl; Carbanions, α-methyl-α-oxybenzyl, configurational stability; Ester-hydroxy ketone rearrangement