174073-19-9

Basic information

• Product Name: Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 1-[(2,6-difluorophenyl)methyl]-5-methyl-6-(4-nitrophenyl)-3-phenyl-
• CAS NO: 174073-19-9
• Molecular Formula: C26H17F2N3O4S
• Molecular Weight: 505.501
• Mol File: 174073-19-9.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 1-[(2,6-difluorophenyl)methyl]-5-methyl-6-(4-nitrophenyl)-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 1-[(2,6-difluorophenyl)methyl]-5-methyl-6-(4-nitrophenyl)-3-phenyl-(174073-19-9)
• EPA Substance Registry System: Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 1-[(2,6-difluorophenyl)methyl]-5-methyl-6-(4-nitrophenyl)-3-phenyl-(174073-19-9)

Safety Data

• Hazardous Substances Data: 174073-19-9(Hazardous Substances Data)

Upstream product

• 103-71-9 phenyl isocyanate 
• 85118-00-9 2,6-Difluorobenzyl bromide 
• 358739-99-8 4-methyl-5-(4-nitro-phenyl)-2-(3-phenyl-ureido)-thiophene-3-carboxylic acid ethyl ester 
• 174072-89-0 2-Amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylic acid ethyl ester 
• 174072-92-5 5-methyl-6-(4-nitrophenyl)-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 697-73-4 2,6-difluorobenzyl chloride 

Downstream Products

• 174072-63-0 6-(4-aminophenyl)-5-(N-benzyl-N-methylaminomethyl)-1-(2,6-difluorobenzyl)-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 481049-95-0 N-(4-{5-{[benzyl(methyl)amino]methyl}-1-(2,6-difluorobenzyl)-3-phenyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl}phenyl)-N'-ethylurea 
• 174073-49-5 5-bromomethyl-1-(2,6-difluorobenzyl)-6-(4-nitrophenyl)-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 481049-97-2 5-(N-benzyl-N-methylaminomethyl)-1-(2,6-difluorobenzyl)-6-[4-[3-(2,4-dimethoxybenzyloxy)ureido]phenyl]-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 481049-98-3 C₃₇H₃₃F₂N₅O₄S 
• 481049-99-4 C₃₈H₃₅F₂N₅O₄S 
• 481049-96-1 1-{4-[5-[(benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-thieno[2,3-d]pyrimidin-6-yl]-phenyl}-3-isopropyl-urea 
• 308831-77-8 5-(N-benzyl-N-methylaminomethyl)-1-(2,6-difluorobenzyl)-6-[4-(3-hydroxyureido)phenyl]-3-phenylthieno[2,3-d]pyrimidine-2,4-(1H,3H)-dione 
• 308831-61-0 N-(4-(5-((benzyl(methyl)amino)methyl)-1-(2,6-difluorobenzyl)-1,2,3,4-tetrahydro-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl)phenyl)-N'-methoxyurea 

Relevant articles and documents

PREMATURE OVULATION PREVENTIVE AGENT

The present invention provides a premature ovulation inhibitor for use in in vitro fertilization or embryo transfer process, which contains a nonpeptidic compound having a gonadotropin releasing hormone antagonistic action. The premature ovulation inhibitor for use in in vitro fertilization or embryo transfer process of the present invention is low toxic, permits oral administration, and has a superior inhibitory effect on premature ovulation in in vitro fertilization or embryo transfer process.

MEDICINAL SOLUTIONS

The present invention relates to a pharmaceutical solution containing a physiologically active non-peptide substance, an organic acid and a biocompatible organic solvent, and provides a pharmaceutical solution wherein a physiologically active non-peptide

Synthesis and structure-activity relationships of thieno[2,3-d]pyrimidine-2,4-dione derivatives as potent GnRH receptor antagonists

The synthesis and SAR studies of thieno[2,3-d]pyrimidine-2,4-diones as human GnRH receptor antagonists to treat reproductive diseases are discussed. It was found that the 2-(2-pyridyl)ethyl group on the 5-aminomethyl functionality of the core structure wa