174195-98-3Relevant articles and documents
COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS
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Paragraph 00950; 00951; 00956; 00957, (2019/01/10)
The present disclosure, among other things, provides technologies for synthesis, including reagents and methods for stereoselective synthesis. In some embodiments, the present disclosure provides compounds useful as chiral auxiliaries. In some embodiments, the present disclosure provides reagents and methods for oligonucleotide synthesis. In some embodiments, the present disclosure provides reagents and methods for chirally controlled preparation of oligonucleotides. In some embodiments, technologies of the present disclosure are particularly useful for constructing challenging internucleotidic linkages, providing high yields and stereoselectivity.
Enantioselective reduction of ketones with borane catalyzed by cyclic β-amino alcohols prepared from proline
Demir, Ayhan S.,Mecitoglu, Idris,Tanyeli, Cihangir,Guelbeyaz, Volkan
, p. 3359 - 3364 (2007/10/03)
New catalysts have been prepared from (S)- and (R)-proline and the asymmetric borane reduction of prochiral ketones using these catalysts has been studied. The secondary alcohols were obtained in 76-95% yield with 57-96% enantiomeric excesses.
