174485-41-7 Usage
Description
1,5-BIS-(4-FLUORO-PHENYL)-PENTAN-3-ONE is a chemical compound with the molecular formula C17H16F2O, belonging to the group of ketones and being a derivative of pentanone. It is a white to light yellow solid with a melting point of around 60-62°C and a boiling point of 335.4°C. 1,5-BIS-(4-FLUORO-PHENYL)-PENTAN-3-ONE is known for its potential applications in medicinal chemistry and drug design due to its structural properties and biological activities, playing a significant role in the development of various therapeutic agents and serving as an important intermediate for the synthesis of a wide range of organic compounds.
Uses
Used in Pharmaceutical Production:
1,5-BIS-(4-FLUORO-PHENYL)-PENTAN-3-ONE is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of therapeutic agents with desired biological activities.
Used in Organic Synthesis:
1,5-BIS-(4-FLUORO-PHENYL)-PENTAN-3-ONE is used as a reagent in organic synthesis for its capacity to facilitate the creation of a wide range of organic compounds, enhancing the diversity and complexity of chemical libraries.
Used in Medicinal Chemistry and Drug Design:
1,5-BIS-(4-FLUORO-PHENYL)-PENTAN-3-ONE is used as a structural component in medicinal chemistry and drug design for its potential to influence the properties and efficacy of new therapeutic agents, contributing to advancements in the treatment of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 174485-41-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,4,8 and 5 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 174485-41:
(8*1)+(7*7)+(6*4)+(5*4)+(4*8)+(3*5)+(2*4)+(1*1)=157
157 % 10 = 7
So 174485-41-7 is a valid CAS Registry Number.
174485-41-7Relevant articles and documents
Highly productive α-alkylation of ketones with alcohols mediated by an Ir-oxalamidato/solid base catalyst system
Maeda, Hironori,Nara, Hideki,Shimizu, Hideo
supporting information, p. 2772 - 2779 (2020/12/29)
An Ir-oxalamidato complex in combination with a solid base (e.g., magnesium aluminometasilicate/Ca(OH)2) significantly improved the catalyst productivity in α-alkylation of methyl ketones with primary alcohols. Optimization through systematic variation of the oxalamidato ligand led to a practical turnover number (TON) of 10 000.40 000.
A Radical Approach to Anionic Chemistry: Synthesis of Ketones, Alcohols, and Amines
Ni, Shengyang,Padial, Natalia M.,Kingston, Cian,Vantourout, Julien C.,Schmitt, Daniel C.,Edwards, Jacob T.,Kruszyk, Monika M.,Merchant, Rohan R.,Mykhailiuk, Pavel K.,Sanchez, Brittany B.,Yang, Shouliang,Perry, Matthew A.,Gallego, Gary M.,Mousseau, James J.,Collins, Michael R.,Cherney, Robert J.,Lebed, Pavlo S.,Chen, Jason S.,Qin, Tian,Baran, Phil S.
supporting information, p. 6726 - 6739 (2019/05/06)
Historically accessed through two-electron, anionic chemistry, ketones, alcohols, and amines are of foundational importance to the practice of organic synthesis. After placing this work in proper historical context, this Article reports the development, f
Enantio- and diastereoselective catalytic mannich-type reaction of a glycine schiff base using a chiral two-center phase-transfer catalyst
Okada, Akihiro,Shibuguchi, Tomoyuki,Ohshima, Takashi,Masu, Hyuma,Yamaguchi, Kentaro,Shibasaki, Masakatsu
, p. 4564 - 4567 (2007/10/03)
(Chemical Equation Presented) Optically active α,β-diamino acids are prepared under asymmetric phase-transfer reaction conditions from a glycine Schiff base and N-protected imines with a tartrate-derived diammonium salt (TaDiAS) as the phase-transfer cata
