174729-13-6

Basic information

• Product Name: C₄₄H₄₅Cl₆N₃O₁₆
• Synonyms: C₄₄H₄₅Cl₆N₃O₁₆
• CAS NO: 174729-13-6
• Molecular Weight: 1084.57
• Mol File: 174729-13-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₄H₄₅Cl₆N₃O₁₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₄H₄₅Cl₆N₃O₁₆(174729-13-6)
• EPA Substance Registry System: C₄₄H₄₅Cl₆N₃O₁₆(174729-13-6)

Safety Data

• Hazardous Substances Data: 174729-13-6(Hazardous Substances Data)

Upstream product

• 79898-19-4 (2R,3S)-3-phenyloxiranecarboxylic acid 
• 174847-58-6 C₄₄H₄₄Cl₆O₁₆ 
• 103-26-4 Methyl cinnamate 
• 115794-67-7 methyl (2R,3S)-3-phenylglycidate 
• 124605-43-2 (2S,3R)-(-)-methyl 3-hydroxy-3-phenyl-2-((p-tolylsulfonyl)oxy)propionate 
• 174729-14-7 13-O-((2S,3R)-3-bromo-2-hydroxy-3-phenylpropionyl)-7,10-O,O'-bis(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin 
• 174729-12-5 13-O-((2R,3R)-3-phenylglycidoyl)-7,10-O,O'-bis(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin 
• 99528-64-0 cis-2,3-epoxy-3-phenyl-1-propanoic acid 

Downstream Products

• 114915-20-7 Docetaxel 
• 114915-14-9 7,10-bis-O-(2,2,2-trichloroethoxycarbonyl)docetaxel 

Relevant articles and documents

Synthesis of taxoids 4. Novel and versatile methods for preparation of new taxoids by employing cis- or trans-phenyl glycidic acid

A novel route to the synthesis of docetaxel using esterification of (2R,3R)-or (2R,3S)-glycidic acid with 7,10-bis-O-(2,2,2- trichloroethoxycarbonyl)-10-deacetylbaccatin III is described. Related novel taxoids which have new side chains were synthesized from these synthetic intermediates.