17553-89-8

Basic information

• Product Name: (7AR)-7A-METHYL-2,3,7,7A-TETRAHYDRO-1H-INDENE-1,5(6H)-DIONE
• Synonyms: HAJOS-PARRISH KETONE, (R)-(-)-ISOMER;(7AR)-7A-METHYL-2,3,7,7A-TETRAHYDRO-1H-INDENE-1,5(6H)-DIONE;(S)-(3-Acetyl-Triphenylphosphoranylidene)-4-Phenyl-Oxazolidin-2-One;(R)-(-)-2,3,7,7a-Tetrahydro-7a-methyl-1H-indene-1,5(6H)-dione;(R)-(-)-2,3,7,7a-Tetrahydro-7a-methyl-1H-indene-1,5(6H)-dione;(R)-7a-Methyl-2,3,7,7a-tetrahydro-1H-indene-1,5(6H)-dione;(R)-(-)-7a-Methyl-2,3,7,7a-tetrahydro-6H-indene-1,5-dione
• CAS NO: 17553-89-8
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2
• Mol File: 17553-89-8.mol
• Article Data: 33

Chemical Properties

• Melting Point: 57.0 to 61.0 °C
• Boiling Point: 310.6°C at 760 mmHg
• Flash Point: 116.2°C
• Appearance: /
• Density: 1.13g/cm³
• Vapor Pressure: 0.000594mmHg at 25°C
• Refractive Index: 1.524
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (7AR)-7A-METHYL-2,3,7,7A-TETRAHYDRO-1H-INDENE-1,5(6H)-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: (7AR)-7A-METHYL-2,3,7,7A-TETRAHYDRO-1H-INDENE-1,5(6H)-DIONE(17553-89-8)
• EPA Substance Registry System: (7AR)-7A-METHYL-2,3,7,7A-TETRAHYDRO-1H-INDENE-1,5(6H)-DIONE(17553-89-8)

Safety Data

• Hazardous Substances Data: 17553-89-8(Hazardous Substances Data)

Usage

General Description

(7AR)-7A-METHYL-2,3,7,7A-TETRAHYDRO-1H-INDENE-1,5(6H)-DIONE is a chemical compound that belongs to the category of indene derivatives. It is a tetrahydroindene with a methyl group attached to the 7A position. (7AR)-7A-METHYL-2,3,7,7A-TETRAHYDRO-1H-INDENE-1,5(6H)-DIONE is a yellow crystalline solid with potential applications in the field of organic synthesis and medicinal chemistry. It possesses unique structural and chemical properties that make it a valuable building block for the synthesis of various molecules. Its specific biological and pharmacological activities are yet to be fully elucidated, but its structural features suggest potential interactions with biological targets. Further research on (7AR)-7A-METHYL-2,3,7,7A-TETRAHYDRO-1H-INDENE-1,5(6H)-DIONE is necessary to explore its potential applications in different fields.

InChI:InChI=1/C10H12O2/c1-10-5-4-8(11)6-7(10)2-3-9(10)12/h6H,2-5H2,1H3/t10-/m1/s1

Upstream product

• 99780-84-4 (7aR)-1t-hydroxy-7a-methyl-(7ar)-1,2,3,6,7,7a-hexahydro-inden-5-one 
• 19576-08-0 (+/-)-7a-methyl-2,3,7,7a,tetrahydro-1H-indene-1,5(6H)-dione 
• 25112-78-1 2-methyl-2-(3-oxobutyl)-1,3-cyclopentanedione 
• 147-85-3 L-proline 
• 17553-88-7 (1R,7aR)-3,6,7,7a-tetrahydro-1-hydroxy-7a-methyl-1H-inden-5(2H)-one 
• 765-69-5 2-Methylcyclopentane-1,3-dione 
• 78-94-4 methyl vinyl ketone 
• 35544-95-7 (3aR,7aR)-3a-hydroxy-7a-methylperhydroindene-1,5-dione 
• 16271-49-1 (1S,7aS)-1-hydroxy-7a-methyl-2,3,7,7a-tetrahydro-1H-inden-5(6H)-one 
• 33879-04-8 (+)-(3aS,7aS)-2,3,3a,4,7,7a-hexahydro-3a-hydroxy-7a-methyl-1H-indene-1,5(6H)-dione 
• 16271-45-7 rac.-7,7a-Dihydro-1β-hydroxy-7aβ-methyl-5(6H)-indanon-hydrogenphthalat 
• 16271-49-1 1β-hydroxy-7aβ-methyl-2,3,7,7a-tetrahydro-1H-inden-5(6H)-one 
• 344-25-2 D-Prolin 
• 1120-72-5 2-Methylcyclopentanone 

Downstream Products

• 105764-24-7 (-)-(7aR)-4-<(phenylthio)methyl>-5,6,7,7a-tetrahydro-7a-methylindan-1,5-dione 
• 358657-53-1 (7aR,1R)-4-(2-benzyloxyethyl)-7a-methyl-5-oxo-2,3,5,6,7,7a-hexahydro-1H-inden-1-ol, pivaloate ester 
• 358657-64-4 2,2-Dimethyl-propionic acid (1R,3aR,4R,7aR)-4-(2-benzyloxy-ethyl)-7a-methyl-5-oxo-octahydro-inden-1-yl ester 
• 149789-96-8 (1R,3aS,4S,5R,7aR)-5-Benzyloxy-4-benzyloxymethyl-1-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-4-(2-trimethylsilanyl-ethoxymethoxy)-octahydro-indene 
• 149790-00-1 Toluene-4-sulfonic acid (1R,3aS,4S,5R,7aR)-1-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-7a-methyl-4-(2-trimethylsilanyl-ethoxymethoxy)-octahydro-inden-4-ylmethyl ester 
• 105764-29-2 (+)-<1(R)-methyl-2(R)-hydroxy-5(R)-(1(R)-((tosyloxy)methyl)-5-methylhexyl)cyclopentyl>acetaldehyde ethylene acetal 
• 105764-30-5 (+)-<1(R)-methyl-2(R)-((methoxymethyl)oxy)-5(R)-(1(R)-((tosyloxy)methyl)-5-methylhexyl)cyclopentyl>acetaldehyde ethylene acetal 
• 105764-26-9 (-)-(3aR,4R,7aR)-4-<(phenylsulfonyl)methyl>-3a,4,5,6,7,7a-hexahydro-7a-methylindan-1,5-dione 
• 105764-25-8 (-)-(7aR)-4-<(phenylsulfonyl)methyl>-5,6,7,7a-tetrahydro-7a-methylindan-1,5-dione 
• 96843-36-6 (3aR,4R,7aR)-5,5-(ethylenedioxy)-1-<(phenylthio)methylene>-4-(4-methylpentyl)-3a,4,5,6,7,7a-hexahydro-7a-methylindan 
• 96894-96-1 (+)-(3aR,4R,7aR)-5,5-(ethylenedioxy)-1(Z)-<(phenylsulfonyl)methylene>-4-(4-methylpentyl)-3a,4,5,6,7,7a-hexahydro-7a-methylindan 
• 96843-37-7 (-)-(3aR,4R,7aR)-5,5-(ethylenedioxy)-1(E)-<(phenylsulfonyl)methylene>-4-(4-methylpentyl)-3a,4,5,6,7,7a-hexahydro-7a-methylindan 
• 131557-14-7 (S)-1-<(3aR,7S,7aR)-3a-methyl-3,6-dioxohexahydroindan-7-yl>-4-<<(4-methylphenyl)sulfonyl>oxy>butan-1-ol acetate 
• 133709-58-7 (1R,2R,8aR)-2-hydroxy-2-methyl-1-<3-<(1,1-dimethylethyl)-diphenylsilyloxy>propyl>-8-oxo-1,2,3,4,6,7,8,8a-octahydronaphthalene 

Relevant articles and documents

Desymmetrisation of: Meso -diones promoted by a highly recyclable polymer-supported chiral phosphoric acid catalyst

A polystyrene-supported BINOL-derived chiral phosphoric acid has been applied to the desymmetrisation of meso-diones to produce enantioenriched cyclohexenones. The catalytic resin has proven highly active and robust, giving rise to Hajos-Parrish or Wieland-Miescher type products in good yields and enantioselectivities, while allowing for extended recycling.

Lipase-catalyzed domino Michael-aldol reaction of 2-methyl-1,3-cycloalkanedione and methyl vinyl ketone for the synthesis of bicyclic compounds

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A practical protocol for asymmetric synthesis of wieland-miescher and hajos-parrish ketones catalyzed by a simple chiral primary amine

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