175676-65-0 Usage
Description
2-(Trifluormethoxy)phenylboronic acid is a chemical compound characterized by its white to light brown solid appearance. It may contain varying amounts of anhydride and is known for its unique chemical properties, making it a valuable reagent in various applications.
Uses
Used in Pharmaceutical Industry:
2-(Trifluormethoxy)phenylboronic acid is used as a reagent for the preparation of ERβ receptor, which is selective towards 4-hydroxybiphenyls. This application is significant in the development of targeted therapies and drugs for specific conditions, potentially improving treatment outcomes and patient care.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-(Trifluormethoxy)phenylboronic acid is utilized in the Suzuki reaction, a widely employed method for the formation of carbon-carbon bonds. This reaction is crucial in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and advanced materials, contributing to the advancement of these industries.
Overall, 2-(Trifluormethoxy)phenylboronic acid plays a vital role in both the pharmaceutical and chemical synthesis industries, showcasing its versatility and importance in modern science and technology.
Check Digit Verification of cas no
The CAS Registry Mumber 175676-65-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,6,7 and 6 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 175676-65:
(8*1)+(7*7)+(6*5)+(5*6)+(4*7)+(3*6)+(2*6)+(1*5)=180
180 % 10 = 0
So 175676-65-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H6BF3O3/c9-7(10,11)14-6-4-2-1-3-5(6)8(12)13/h1-4,12-13H
175676-65-0Relevant articles and documents
Copper-Catalyzed Monoorganylation of Trialkyl Borates with Functionalized Organozinc Pivalates
Fu, Ying,Gou, Bei-Lei,Shi, Chun-Zhao,Du, Zhengyin,Shen, Tong
, p. 4253 - 4257 (2018/09/18)
Organozinc pivalates, a recently developed air- and moisture-stable organozinc species, were found for the first time as excellent organometallic species in the monoorganylation of trialkyl borates whereby boronic acids were prepared in high yields. The significant advantage of organozinc pivalates over another previously employed organometallic reagents, e. g., organolithium reagents, Grignard reagents and organozinc halides, is that the generation of multiorganylation byproducts such as borinic acids and trialkylboranes were completely suppressed. Additionally, the in situ generated boronates could be directly arranged into Suzuki-Miyaura type cross-coupling reactions to produce biaryls in high yields.
SUBSTITUTED TRIAZOLES AS SODIUM CHANNEL BLOCKERS
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Page/Page column 34-35, (2008/06/13)
Substituted triazole compounds represented by Formula I, II or III, or pharmaceutically acceptable salts thereof. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other the
BIARYL SUBSTITUTED TRIAZOLES AS SODIUM CHANNEL BLOCKERS
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Page 33-34, (2008/06/13)
Biaryl substituted triazole compounds represented by Formula I, II or III, or pharmaceutically acceptable salts thereof, and a process for making such compounds and salts thereof. Pharmaceutical compositions comprise an effective amount of the instant com
