306936-00-5 Usage
General Description
5-[2-(Trifluoromethoxy)phenyl]-2-furaldehyde is a chemical compound with the molecular formula C11H7F3O3. It is a furan derivative with a trifluoromethoxy and aldehyde functional groups attached to a phenyl ring. 5-[2-(TRIFLUOROMETHOXY)PHENYL]-2-FURALDEHYDE is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is also used as a building block for the preparation of various functional materials and fine chemicals. Its unique structure and properties make it a valuable tool in chemical research and development, with potential applications in industries such as pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 306936-00-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,6,9,3 and 6 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 306936-00:
(8*3)+(7*0)+(6*6)+(5*9)+(4*3)+(3*6)+(2*0)+(1*0)=135
135 % 10 = 5
So 306936-00-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H7F3O3/c13-12(14,15)18-11-4-2-1-3-9(11)10-6-5-8(7-16)17-10/h1-7H
306936-00-5Relevant articles and documents
Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid
Pfefferkorn, Jeffrey A.,Greene, Meredith L.,Nugent, Richard A.,Gross, Rebecca J.,Mitchell, Mark A.,Finzel, Barry C.,Harris, Melissa S.,Wells, Peter A.,Shelly, John A.,Anstadt, Robert A.,Kilkuskie, Robert E.,Kopta, Laurice A.,Schwende, Francis J.
, p. 2481 - 2486 (2007/10/03)
A novel series of nonnucleoside HCV NS5B polymerase inhibitors were prepared from (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid, a high throughput screening lead. SAR studies combined with structure based drug design focusing on the southern heterobiaryl region of the template led to the synthesis of several potent and orally bioavailable lead compounds. X-ray crystallography studies were also performed to understand the interaction of these inhibitors with HCV NS5B polymerase.
