177753-08-1

Basic information

• Product Name: N'-acetyl-2S-[2-²H]-kynurenine
• Synonyms: N'-acetyl-2S-[2-²H]-kynurenine
• CAS NO: 177753-08-1
• Molecular Weight: 251.246
• Mol File: 177753-08-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N'-acetyl-2S-[2-²H]-kynurenine(CAS DataBase Reference)
• NIST Chemistry Reference: N'-acetyl-2S-[2-²H]-kynurenine(177753-08-1)
• EPA Substance Registry System: N'-acetyl-2S-[2-²H]-kynurenine(177753-08-1)

Safety Data

• Hazardous Substances Data: 177753-08-1(Hazardous Substances Data)

Upstream product

• 343-65-7 Kynurenine 
• 177753-07-0 N,N'-diacetyl-(2-⁽²⁾H)-(2RS)-kynurenine 

Downstream Products

• 177753-06-9 2S-[2-²H]-kynurenine 

Relevant articles and documents

Two syntheses of 2S-[2-2H]-kynurenine

The synthesis of 2S-[2-2H]-kynurenine is described using two different routes. Diacetylation/racemisation of racemic kynurenine in deuterium oxide followed by acylase catalysed resolution is the most direct route. The alternative is to prepare 2S-[2-2H]-tryptophan by a similar procedure and then convert this through to 2S-[2-2H]-kynurenine via ozonolysis.