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17826-12-9

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17826-12-9 Usage

Description

(6-bromo-indol-3-yl)-oxo-acetic acid ethyl ester is a synthetic chemical compound featuring a bromine-substituted indole ring and a keto-acetic acid moiety. It serves as an ethyl ester and is utilized in organic chemistry research, acting as a building block for the synthesis of more complex molecules. This versatile compound holds potential for applications in the development of pharmaceuticals and agrochemicals, although further research is necessary to fully comprehend its properties and possible uses. Careful handling and usage are advised due to potential hazards associated with the compound.

Uses

Used in Organic Chemistry Research:
(6-bromo-indol-3-yl)-oxo-acetic acid ethyl ester is used as a building block for the synthesis of complex molecules, contributing to the advancement of organic chemistry.
Used in Pharmaceutical Development:
In the pharmaceutical industry, (6-bromo-indol-3-yl)-oxo-acetic acid ethyl ester is used as a potential precursor for the development of new drugs, given its unique structure and synthetic nature.
Used in Agrochemical Development:
Similarly, in the agrochemical sector, (6-bromo-indol-3-yl)-oxo-acetic acid ethyl ester is used as a starting material for the creation of novel compounds with potential applications in agriculture.

Check Digit Verification of cas no

The CAS Registry Mumber 17826-12-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,8,2 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 17826-12:
(7*1)+(6*7)+(5*8)+(4*2)+(3*6)+(2*1)+(1*2)=119
119 % 10 = 9
So 17826-12-9 is a valid CAS Registry Number.

17826-12-9Downstream Products

17826-12-9Relevant articles and documents

IMMUNOCONJUGATES TARGETING HER2

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Paragraph 0366-0367, (2020/10/09)

The invention provides an immunoconjugate of formula (I) or (II). Antibody-adjuvant immunoconjugates of the invention, comprising an antibody construct that has an antigen binding domain that binds human epidermal growth factor receptor 2 ("HER2") linked to one or more adjuvants, demonstrate superior pharmacological properties over conventional antibody conjugates. The invention further provides compositions comprising and methods of treating cancer with the immunoconjugate.

IMMUNOCONJUGATES TARGETING PD-L1

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Paragraph 0299; 0300, (2020/10/09)

The invention provides an immunoconjugate of formula (I) or (II). Antibody-adjuvant immunoconjugates of the invention, comprising an antibody construct that has an antigen binding domain that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants, demonstrate superior pharmacological properties over conventional antibody conjugates. The invention further provides compositions comprising and methods of treating cancer with the immunoconjugate.

IMMUNOCONJUGATES

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Paragraph 0375; 0376, (2019/12/04)

The invention provides an immunoconjugate comprising (a) an antibody construct comprising (i) an antigen binding domain and (ii) an Fc domain and (b) 1-8 adjuvant cores, wherein each adjuvant core is covalently bonded to the antibody construct via a linker, wherein each adjuvant core comprises a 2-amino nitrogen moiety with a pendant nitrogen atom and a point of attachment of the linker to the adjuvant core, and wherein the distance between the pendant nitrogen atom and the point of attachment of the linker is greater than about 5 ?. The invention also provides methods for treating cancer with the immunoconjugates.

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