178424-17-4

Basic information

• Product Name: 1-tert-butyl 4-ethyl 3-hydroxy-1H-pyrazole-1,4- dicarboxylate
• Synonyms: 1-tert-butyl 4-ethyl 3-hydroxy-1H-pyrazole-1,4- dicarboxylate;1H-Pyrazole-1,4-dicarboxylic acid, 2,3-dihydro-3-oxo-, 1-(1,1-diMethylethyl) 4-ethyl ester;Ethyl 3-hydroxy-1-Boc-pyrazole-4-carboxylate
• CAS NO: 178424-17-4
• Molecular Formula: C11H17N2O5
• Molecular Weight: 257.26308
• Mol File: 178424-17-4.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-tert-butyl 4-ethyl 3-hydroxy-1H-pyrazole-1,4- dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-tert-butyl 4-ethyl 3-hydroxy-1H-pyrazole-1,4- dicarboxylate(178424-17-4)
• EPA Substance Registry System: 1-tert-butyl 4-ethyl 3-hydroxy-1H-pyrazole-1,4- dicarboxylate(178424-17-4)

Safety Data

• Hazardous Substances Data: 178424-17-4(Hazardous Substances Data)

Usage

General Description

1-tert-butyl 4-ethyl 3-hydroxy-1H-pyrazole-1,4-dicarboxylate is an organic compound with the molecular formula C15H23N3O5. It is a pyrazole derivative that contains a tert-butyl group, an ethyl group, and two carboxylate groups. This chemical compound is commonly used in pharmaceutical research and organic synthesis. It may have potential applications in the development of pharmaceutical drugs, due to its ability to interact with biological systems and potentially exhibit pharmacological properties. Its precise uses and properties may vary depending on the specific application and context in which it is used.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 7251-53-8 3-hydroxypyrazole-4-carboxylic acid ethyl ester 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 

Downstream Products

• 178424-16-3 3-[[(4-methoxyphenyl)methyl]oxy]pyrazole-4-carboxylic acid ethyl ester 
• 478968-48-8 ethyl 3-methoxy-1H-pyrazole-4-carboxylate 

Relevant articles and documents

PROCESSES FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

The disclosure provides processes for preparing a compound of Formula (I).

CRYSTALLINE FORMS AND COMPOSITIONS OF CFTR MODULATORS

Crystalline Forms of Compound I: and pharmaceutically acceptable salts thereofare disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.

1-(HET)ARYLSULFONYL-(PYRROLIDINE OR PIPERIDINE)-2-CARBOXAMIDE DERIVATIVES AND THEIR USE AS TRPA1 ANTAGONISTS

The invention is concerned with the compounds of formula I and salts thereof and other compounds of formulas II-IX as disclosed herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formulas I-IX as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain or asthma.